Viaminate

Modify Date: 2024-01-09 10:49:53

Viaminate structure	Common Name	Viaminate
	CAS Number	53839-71-7	Molecular Weight	447.61
	Density	1.071 g/cm3	Boiling Point	619.4ºCat 760 mmHg
	Molecular Formula	C₂₉H₃₇NO₃	Melting Point	177-182 °C
	MSDS	N/A	Flash Point	328.4ºC

Use of Viaminate

Viaminate is a derivative of Retinoic acid, which is used for the treatment of severe acne and other keratinization disorders.

Name	ethyl 4-[[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoyl]amino]benzoate
Synonym	More Synonyms

Description	Viaminate is a derivative of Retinoic acid, which is used for the treatment of severe acne and other keratinization disorders.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	Viaminate is an amide compound formed by Tretinoin and Ethyl p-aminobenzoate, in which the end group of Tretinoin is transformed into amide and ester chain[1].
References	[1]. Zhang H, et al. Fatal Hepatotoxicity Due to Viaminate. Am J Med Sci. 2018 Jul;356(1):84-86.

Density	1.071 g/cm3
Boiling Point	619.4ºCat 760 mmHg
Melting Point	177-182 °C
Molecular Formula	C₂₉H₃₇NO₃
Molecular Weight	447.61
Flash Point	328.4ºC
Exact Mass	447.27700
PSA	55.40000
LogP	7.40640

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VH6409600

CHEMICAL NAME :: Retinamide, N-(4-(ethoxycarbonyl)phenyl)-

CAS REGISTRY NUMBER :: 53839-71-7

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C29-H37-N-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 17,331,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8806 mg/kg/2W-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 17,331,1982

Hazard Codes	Xi

N-(4-(Ethoxycarbonyl)phenyl)retinamide

viaminate

4-(Ethoxycarbophenyl)retinamide

4-(Carboethoxyphenyl)retinamide

retinamide ethyl benzoate

Retinamide,N-(4-(ethoxycarbonyl)phenyl)

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Viaminate

Use of Viaminate

Names

Viaminate Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synonyms