Tropinone

Modify Date: 2024-01-02 15:24:55

Tropinone Structure
Tropinone structure
Common Name Tropinone
CAS Number 532-24-1 Molecular Weight 139.195
Density 1.1±0.1 g/cm3 Boiling Point 217.1±0.0 °C at 760 mmHg
Molecular Formula C8H13NO Melting Point 40-44 °C(lit.)
MSDS Chinese USA Flash Point 90.0±0.0 °C

 Use of Tropinone


Tropinone, an alkaloid, acts as a synthetic intermediate to Atropine[1].

 Names

Name tropinone
Synonym More Synonyms

 Tropinone Biological Activity

Description Tropinone, an alkaloid, acts as a synthetic intermediate to Atropine[1].
Related Catalog
References

[1]. Bedewitz MA, et al.  Tropinone synthesis via an atypical polyketide synthase and P450-mediated cyclization. Nat Commun. 2018 Dec 11;9(1):5281. doi: 10.1038/s41467-018-07671-3.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 217.1±0.0 °C at 760 mmHg
Melting Point 40-44 °C(lit.)
Molecular Formula C8H13NO
Molecular Weight 139.195
Flash Point 90.0±0.0 °C
Exact Mass 139.099716
PSA 20.31000
LogP 0.07
Vapour Pressure 0.1±0.4 mmHg at 25°C
Index of Refraction 1.505
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S23-S24/25-S36/37/39-S26-S22
RIDADR 1544
WGK Germany 3
Packaging Group III
Hazard Class 6.1
HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles21

More Articles
Toxicity of field bindweed (Convolvulus arvensis) to mice.

Vet. Hum. Toxicol. 37(5) , 452-4, (1995)

The effects of feeding high and low doses of field bindweed (Convolvulus arvensis) to mice were investigated. Bindweed contains several alkaloids, including pseudotropine, and lesser amounts of tropin...

Synthesis and applications of masked oxo-sulfinamides in asymmetric synthesis.

Org. Biomol. Chem. 10(26) , 5021-31, (2012)

This short perspective reports on the synthesis and applications of a class of chiral amino carbonyl compounds, masked oxo-sulfinamides where the amine is protected with an N-sulfinyl moiety and the c...

Biosynthesis of calystegines: 15N NMR and kinetics of formation in root cultures of Calystegia sepium.

Phytochemistry 62(3) , 325-32, (2003)

Calystegines are nortropane alkaloids bearing between three and five hydroxyl groups in various positions. [15N]Tropinone was administered to root cultures of Calystegia sepium and the incorporation i...

 Synonyms

Tropanon
N-methyl-3-tropanone
8-azabicyclo[3.2.1]octan-3-one, 8-methyl-, (1S,5S)-
8-Methyl-8-azabicyclo[3.2.1]-3-octanone
3-tropinone
tropan-3-one
(1S,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-one
Tropinone
EINECS 208-530-6
Tropinon
Tropanone
3-Tropanone
8-Azabicyclo[3.2.1]octan-3-one, 8-methyl-, (1R,5S)-
(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-one
1αH,5αH-tropan-3-one
8-methyl-8-aza-bicyclo[3.2.1]octan-3-one
MFCD00005549
1αH,5αH-Tropan-3-one (8CI)
TROPIONONE
8-methyl-8-azabicyclo[3.2.1]oct-3-one
8-methyl-8-azabicyclo[3.2.1]octane-3-one
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