Aromadendrin
Modify Date: 2024-01-04 18:04:42
Aromadendrin structure
|
Common Name | Aromadendrin | ||
|---|---|---|---|---|
| CAS Number | 480-20-6 | Molecular Weight | 288.252 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 639.0±55.0 °C at 760 mmHg | |
| Molecular Formula | C15H12O6 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 247.3±25.0 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of AromadendrinDihydrokaempferol is isolated from Bauhinia championii (Benth). Dihydrokaempferol induces apoptosis and inhibits Bcl-2 and Bcl-xL expression. Dihydrokaempferol is a good candidate for new antiarthritic drugs[1]. |
| Name | (+)-dihydrokaempferol |
|---|---|
| Synonym | More Synonyms |
| Description | Dihydrokaempferol is isolated from Bauhinia championii (Benth). Dihydrokaempferol induces apoptosis and inhibits Bcl-2 and Bcl-xL expression. Dihydrokaempferol is a good candidate for new antiarthritic drugs[1]. |
|---|---|
| Related Catalog | |
| Target |
Apoptosis; Bcl-2; Bcl-xL[1] |
| In Vitro | Dihydrokaempferol (0.3-300 μM; 48 hours) has no significant effect on normal synoviocytes, but dependently decreases the viability of RA-FLSs[1]. Dihydrokaempferol (3-30 μM; 48 hours) increases the percentage of apoptotic cells (including early and late apoptotic cells; ~3.8% and ~9.6%, respectively)[1]. Dihydrokaempferol (3-30 μM; 48 hours) promotes Bax and Bad expression and inhibits Bcl-2 and Bcl-xL expression, increases the cleaved fragments of caspase-3, caspase-9 and cleaved PARP[1]. Cell Proliferation Assay[1] Cell Line: Normal synoviocyte cells; RA-FLS cells Concentration: 0.3 μM, 3 μM, 30 μM, 300 μM Incubation Time: 48 hours Result: Decreased the proliferation of RA-FLSs. Apoptosis Analysis[1] Cell Line: RA-FLS cells Concentration: 3 μM, 30 μM Incubation Time: 48 hours Result: Induced apoptosis in RA-FLSs. Western Blot Analysis[1] Cell Line: RA-FLS cells Concentration: 3 μM, 30 μM Incubation Time: 48 hours Result: Promoted Bax and Bad expression, increased the cleaved fragments of caspase-3, caspase-9 and cleaved PARP and inhibited Bcl-2 and Bcl-xL expression. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 639.0±55.0 °C at 760 mmHg |
| Molecular Formula | C15H12O6 |
| Molecular Weight | 288.252 |
| Flash Point | 247.3±25.0 °C |
| Exact Mass | 288.063385 |
| PSA | 107.22000 |
| LogP | 2.42 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.729 |
| Storage condition | ?20°C |
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Aromadendrin CAS#:480-20-6 |
| Literature: Takahashi, Hiroshi; Kubota, Yumiko; Igushi, Mieko; Fang, Lin; Onda, Masayuki Heterocycles, 1986 , vol. 24, # 2 p. 369 - 377 |
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~%
Aromadendrin CAS#:480-20-6 |
| Literature: Takahashi, Hiroshi; Kubota, Yumiko; Igushi, Mieko; Fang, Lin; Onda, Masayuki Heterocycles, 1986 , vol. 24, # 2 p. 369 - 377 |
|
~%
Aromadendrin CAS#:480-20-6 |
| Literature: Takahashi, Hiroshi; Kubota, Yumiko; Igushi, Mieko; Fang, Lin; Onda, Masayuki Heterocycles, 1986 , vol. 24, # 2 p. 369 - 377 |
|
~%
Aromadendrin CAS#:480-20-6 |
| Literature: Takahashi, Hiroshi; Kubota, Yumiko; Igushi, Mieko; Fang, Lin; Onda, Masayuki Heterocycles, 1986 , vol. 24, # 2 p. 369 - 377 |
![1-[2-hydroxy-4,6-bis(methoxymethoxy)phenyl]ethanone structure](https://www.chemsrc.com/caspic/448/65490-09-7.png)
![1-[2,4,6-tris(methoxymethoxy)phenyl]ethanone structure](https://www.chemsrc.com/caspic/413/36804-11-2.png)
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Production of 7-O-methyl aromadendrin, a medicinally valuable flavonoid, in Escherichia coli.
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| 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-, (2R-trans)- |
| Katuranin |
| (2R,3R)-3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one |
| (+)-dihydrokaempferol |
| Aromadedrin |
| Aromadendrin |
| 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-, (2R,3R)- |
| DIHYDROKAEMPFEROL |
- BioBioPha
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- Product Name: Aromadendrin
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- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
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- Purity: 98.0%
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- DC Chemicals Limited
- China
- Product Name: Aromadendrin
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- Purity: 98.0%
- Stocking Period: 3 Day
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- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: aromadedrin
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: DIHYDROKAEMPFEROL
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
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