Eugenitin

Modify Date: 2024-01-02 17:36:57

Eugenitin Structure
Eugenitin structure
Common Name Eugenitin
CAS Number 480-12-6 Molecular Weight 220.22100
Density 1.267g/cm3 Boiling Point 402.2ºC at 760 mmHg
Molecular Formula C12H12O4 Melting Point N/A
MSDS N/A Flash Point 158.8ºC

 Use of Eugenitin


Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD50=39.9 μM. Eugenitin has low cytotoxicity (IC50 >131 μM) against several human cancer cell lines[1].

 Names

Name 5-hydroxy-7-methoxy-2,6-dimethylchromen-4-one
Synonym More Synonyms

 Eugenitin Biological Activity

Description Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD50=39.9 μM. Eugenitin has low cytotoxicity (IC50 >131 μM) against several human cancer cell lines[1].
Related Catalog
Target

LD50: 39.9 μM (Leishmania major)[1]

References

[1]. Andrioli W J, et al. Mycoleptones A–C and polyketides from the endophyte Mycoleptodiscus indicus[J]. Journal of Natural Products, 2014, 77(1): 70-78.  

 Chemical & Physical Properties

Density 1.267g/cm3
Boiling Point 402.2ºC at 760 mmHg
Molecular Formula C12H12O4
Molecular Weight 220.22100
Flash Point 158.8ºC
Exact Mass 220.07400
PSA 59.67000
LogP 2.12400
Vapour Pressure 4.8E-07mmHg at 25°C
Index of Refraction 1.58

 Synthetic Route

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Eugenitin Structure

Eugenitin

CAS#:480-12-6

Literature: Mukerjee; Seshadri Proceedings - Indian Academy of Sciences, Section A, 1953 , # 38 p. 207,217 Full Text Show Details Whalley Journal of the American Chemical Society, 1952 , vol. 74, p. 5795

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Eugenitin Structure

Eugenitin

CAS#:480-12-6

Literature: Schoenberg et al. Journal of the American Chemical Society, 1953 , vol. 75, p. 4992,4994 Journal of the American Chemical Society, 1955 , vol. 77, p. 6721

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Eugenitin Structure

Eugenitin

CAS#:480-12-6

Literature: Schoenberg et al. Journal of the American Chemical Society, 1953 , vol. 75, p. 4992,4994 Journal of the American Chemical Society, 1955 , vol. 77, p. 6721

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Eugenitin Structure

Eugenitin

CAS#:480-12-6

Literature: Schoenberg et al. Journal of the American Chemical Society, 1953 , vol. 75, p. 4992,4994 Journal of the American Chemical Society, 1955 , vol. 77, p. 6721

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Eugenitin Structure

Eugenitin

CAS#:480-12-6

Literature: Mukerjee et al. Proceedings - Indian Academy of Sciences, Section A, 1953 , # 37 p. 127,142

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Eugenitin Structure

Eugenitin

CAS#:480-12-6

Literature: Mukerjee et al. Proceedings - Indian Academy of Sciences, Section A, 1953 , # 37 p. 127,142

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Detail
Literature: Mukerjee; Seshadri Proceedings - Indian Academy of Sciences, Section A, 1953 , # 38 p. 207,217

 Synonyms

Eugenitin
Eugenetin
5-Hydroxy-7-methoxy-2,6-dimethyl-chromen-4-on
4H-1-Benzopyran-4-one,5-hydroxy-7-methoxy-2,6-dimethyl
5-hydroxy-7-methoxy-2,6-dimethylchromone
5-hydroxy-7-methoxy-2,6-dimethyl-chromen-4-one
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