Asperosaponin VI

Modify Date: 2024-01-02 15:01:10

Asperosaponin VI structure	Common Name	Asperosaponin VI
	CAS Number	39524-08-8	Molecular Weight	929.096
	Density	1.43	Boiling Point	990.2±65.0 °C at 760 mmHg
	Molecular Formula	C₄₇H₇₆O₁₈	Melting Point	N/A
	MSDS	N/A	Flash Point	282.1±27.8 °C

Use of Asperosaponin VI

Asperosaponin VI, A saponin component from Dipsacus asper wall, induces osteoblast differentiation through BMP‐2/p38 and ERK1/2 pathway[1]. Asperosaponin Ⅵ inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bcl-2/Bax ratio and decreasing active caspase-3 expression, as well as enhancing of p-Akt and p-CREB[2].

Name	Akebia saponin D
Synonym	More Synonyms

Description	Asperosaponin VI, A saponin component from Dipsacus asper wall, induces osteoblast differentiation through BMP‐2/p38 and ERK1/2 pathway[1]. Asperosaponin Ⅵ inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bcl-2/Bax ratio and decreasing active caspase-3 expression, as well as enhancing of p-Akt and p-CREB[2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cardiovascular Disease
References	[1]. Niu Y, et al. Asperosaponin VI, a saponin component from Dipsacus asper wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway. Phytother Res. 2011 Nov;25(11):1700-6. [2]. Li C, et al. Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways. Eur J Pharmacol. 2010 Dec 15;649(1-3):100-7.

Description

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cardiovascular Disease

References

[1]. Niu Y, et al. Asperosaponin VI, a saponin component from Dipsacus asper wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway. Phytother Res. 2011 Nov;25(11):1700-6.

[2]. Li C, et al. Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways. Eur J Pharmacol. 2010 Dec 15;649(1-3):100-7.

Density	1.43
Boiling Point	990.2±65.0 °C at 760 mmHg
Molecular Formula	C₄₇H₇₆O₁₈
Molecular Weight	929.096
Flash Point	282.1±27.8 °C
Exact Mass	928.503174
PSA	294.98000
LogP	4.18
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.627