2-(Trifluoromethyl)-2-hydroxypropionic acid

Modify Date: 2024-01-14 13:19:08

2-(Trifluoromethyl)-2-hydroxypropionic acid Structure
2-(Trifluoromethyl)-2-hydroxypropionic acid structure
Common Name 2-(Trifluoromethyl)-2-hydroxypropionic acid
CAS Number 374-35-6 Molecular Weight 158.076
Density 1.5±0.1 g/cm3 Boiling Point 247.4±35.0 °C at 760 mmHg
Molecular Formula C4H5F3O3 Melting Point 110ºC
MSDS N/A Flash Point 103.4±25.9 °C

 Names

Name 2-(Trifluoromethyl)-2-hydroxypropionic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 247.4±35.0 °C at 760 mmHg
Melting Point 110ºC
Molecular Formula C4H5F3O3
Molecular Weight 158.076
Flash Point 103.4±25.9 °C
Exact Mass 158.019073
PSA 57.53000
LogP 1.90
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.384
Storage condition Refrigerator

 Safety Information

Hazard Codes C: Corrosive;
Risk Phrases R34
Safety Phrases 26-36/37/39-45
RIDADR UN 3261
HS Code 2918199090

 Synthetic Route

2-(Trifluoromethyl)-2-hydroxypropionic acid Structure

2-(Trifluoromet...

CAS#:374-35-6

~%

2-(Trifluoromethyl)-2-hydroxypropionic acid Structure

2-(Trifluoromet...

CAS#:374-35-6

Literature: Darrall et al. Journal of the Chemical Society, 1951 , p. 2329,2330

~45%

2-(Trifluoromethyl)-2-hydroxypropionic acid Structure

2-(Trifluoromet...

CAS#:374-35-6

Literature: Fuhshuku, Ken-Ichi; Watanabe, Shunsuke; Nishii, Tetsuro; Ishii, Akihiro; Asano, Yasuhisa Journal of Molecular Catalysis B: Enzymatic, 2014 , vol. 102, p. 115 - 119

~35%

2-(Trifluoromethyl)-2-hydroxypropionic acid Structure

2-(Trifluoromet...

CAS#:374-35-6

Literature: Tosoh Corporation Patent: EP1422226 A1, 2004 ; Location in patent: Page 12 ;

~%

2-(Trifluoromethyl)-2-hydroxypropionic acid Structure

2-(Trifluoromet...

CAS#:374-35-6

Literature: Konigsberger, Kurt; Prasad, Kapa; Repic, Oljan Tetrahedron Asymmetry, 1999 , vol. 10, # 4 p. 679 - 687

 Customs

HS Code 2918199090
Summary 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Synonyms

2-Hydroxy-2-(trifluoromethyl)propionic Acid
TFM-LA
MFCD00190646
Propanoic acid, 3,3,3-trifluoro-2-hydroxy-2-methyl-
3,3,3-Trifluoro-2-hydroxy-2-methylpropionic Acid
3,3,3-Trifluoro-2-hydroxy-2-methylpropanoic acid
2-hydroxy-2-methyl-3,3,3-trifluoropropanoic acid
RARECHEM AL BO 0412
3,3,3-TRIFLUORO-2-HYDROXYISOBUTYRIC ACID