A201A

Modify Date: 2023-01-16 15:19:18

A201A Structure
A201A structure
Common Name A201A
CAS Number 37305-78-5 Molecular Weight 802.82500
Density 1.52g/cm3 Boiling Point N/A
Molecular Formula C37H50N6O14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of A201A


A201A is a aminoacylnucleoside antibiotic with antibacterial activities. A201A is highly effective against Gram-positive and most Gram-negative anaerobic bacteria. A201A inhibits tRNA accommodation during translation[1][2].

 Names

Name (E)-3-[4-[(5Z)-3,4-dihydroxy-5-[2-(3-hydroxy-4,5-dimethoxy-6-methyloxan-2-yl)oxy-1-methoxyethylidene]oxolan-2-yl]oxyphenyl]-N-[5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-2-methylprop-2-enamide
Synonym More Synonyms

 A201A Biological Activity

Description A201A is a aminoacylnucleoside antibiotic with antibacterial activities. A201A is highly effective against Gram-positive and most Gram-negative anaerobic bacteria. A201A inhibits tRNA accommodation during translation[1][2].
Related Catalog
References

[1]. Nie S, et al. Total synthesis of nucleoside antibiotic A201A. J Am Chem Soc. 2014 Mar 19;136(11):4157-60.  

[2]. Wang J, et al. Bioinspired Total Synthesis of Complex Nucleoside Antibiotics A201A, A201D and A201E. Angew Chem Int Ed Engl. 2023 Jan 16;62(3):e202213810.  

 Chemical & Physical Properties

Density 1.52g/cm3
Molecular Formula C37H50N6O14
Molecular Weight 802.82500
Exact Mass 802.33900
PSA 254.42000
LogP 0.03870
Index of Refraction 1.655

 Synonyms

Antibiotic A 201A
A 201A
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