1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid

Modify Date: 2024-01-04 17:46:08

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid Structure
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid structure
Common Name 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid
CAS Number 3719-45-7 Molecular Weight 153.13500
Density 1.381g/cm3 Boiling Point 329.6ºC at 760mmHg
Molecular Formula C7H7NO3 Melting Point N/A
MSDS Chinese USA Flash Point 153.2ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid


1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is from Cordyceps bassiana, which is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid targets to block AP-1-mediated luciferase activity, implying it has an anti-inflammatory function[1].

 Names

Name 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid
Synonym More Synonyms

  Biological Activity

Description 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is from Cordyceps bassiana, which is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid targets to block AP-1-mediated luciferase activity, implying it has an anti-inflammatory function[1].
Related Catalog
References

[1]. Suh W, et al. Chemical Constituents Identified from Fruit Body of Cordyceps bassiana and Their Anti-Inflammatory Activity. Biomol Ther (Seoul). 2017 Mar 1;25(2):165-170.

 Chemical & Physical Properties

Density 1.381g/cm3
Boiling Point 329.6ºC at 760mmHg
Molecular Formula C7H7NO3
Molecular Weight 153.13500
Flash Point 153.2ºC
Exact Mass 153.04300
PSA 59.30000
LogP 0.08350
Index of Refraction 1.577
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26-36/37
RIDADR NONH for all modes of transport
HS Code 2933399090

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles4

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Identification of N1-methyl-2-pyridone-5-carboxamide and N1-methyl-4-pyridone-5-carboxamide as components in urine extracts of individuals consuming coffee.

J. Pharm. Biomed. Anal. 30(3) , 773-80, (2002)

Caffeine metabolites were extracted from urine samples collected 4 h after consumption of a cup of coffee and were separated by high-performance liquid chromatography (HPLC) on a C18 (5 microm) revers...

Urinary excretion of N1-methyl-2-pyridone-5-carboxylic acid and the fate of remaining of trigonelline.

Adv. Exp. Med. Biol. 398 , 599-603, (1996)

Nicotinamide and insulin sensitivity.

Diabetologia 36(4) , 369, (1993)

 Synonyms

1,6-DIHYDRO-1-METHYL-6-OXOPYRIDINE-3-CARBOXYLIC ACID
1-methyl-6-oxopyridine-3-carboxylic acid
Nudifloric acid
1,6-Dihydro-1-methyl-6-oxo-3-pyridinecarboxylic acid
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