5-Nitro-α-oxo-N-(1R)-phenylethyl]-1H-indole-3-acetamide
Modify Date: 2024-01-10 11:00:40
![5-Nitro-α-oxo-N-(1R)-phenylethyl]-1H-indole-3-acetamide Structure](https://www.chemsrc.com/caspic/141/355022-97-8.png)
5-Nitro-α-oxo-N-(1R)-phenylethyl]-1H-indole-3-acetamide structure
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Common Name | 5-Nitro-α-oxo-N-(1R)-phenylethyl]-1H-indole-3-acetamide | ||
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| CAS Number | 355022-97-8 | Molecular Weight | 337.32900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H15N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 5-Nitro-α-oxo-N-(1R)-phenylethyl]-1H-indole-3-acetamideAnxiolytic/nonsedative agent-1 (compound 2b) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic/nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo[1]. |
| Name | 2-(5-Nitro-1H-indol-3-yl)-2-oxo-N-[(1R)-1-phenylethyl]acetamide |
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| Description | Anxiolytic/nonsedative agent-1 (compound 2b) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic/nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo[1]. |
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| References |
| Molecular Formula | C18H15N3O4 |
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| Molecular Weight | 337.32900 |
| Exact Mass | 337.10600 |
| PSA | 107.78000 |
| LogP | 4.05030 |