H-Pro-NHME.HCL

Modify Date: 2024-01-13 12:51:12

H-Pro-NHME.HCL Structure
H-Pro-NHME.HCL structure
Common Name H-Pro-NHME.HCL
CAS Number 33208-98-9 Molecular Weight 164.633
Density N/A Boiling Point N/A
Molecular Formula C6H13ClN2O Melting Point N/A
MSDS Chinese Flash Point N/A

 Names

Name H-Pro-NHME.HCL
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C6H13ClN2O
Molecular Weight 164.633
Exact Mass 164.071640
PSA 41.13000
LogP 1.00610

 MSDS

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: H-Pro-NHMe HCl
Synonyms:(S)-Pyrrolidine-2-carboxylic acid amide hydrochloride

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H302:Harmful if swallowed
H411:Toxic to aquatic life with long lasting effects
P273:Avoid release to the environment

Section3. Composition/information on ingredients.
Ingredient name:H-Pro-NHMe HCl
CAS number:33208-98-9

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula:C6H12N2O.ClH
Molecular weight:164.6

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

HS Code 2933990090

 Synthetic Route

~98%

H-Pro-NHME.HCL Structure

H-Pro-NHME.HCL

CAS#:33208-98-9

Literature: Shendage, Deepak M.; Froehlich, Roland; Haufe, Guenter Organic Letters, 2004 , vol. 6, # 21 p. 3675 - 3678

~%

H-Pro-NHME.HCL Structure

H-Pro-NHME.HCL

CAS#:33208-98-9

Literature: Shendage, Deepak M.; Froehlich, Roland; Haufe, Guenter Organic Letters, 2004 , vol. 6, # 21 p. 3675 - 3678

~29%

H-Pro-NHME.HCL Structure

H-Pro-NHME.HCL

CAS#:33208-98-9

Literature: Nifontov, V. I.; Bel'skaya, N. P.; Chernov, V. A.; Galyamova, I. V.; Khvorova, N. M.; et al. Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 8 p. 577 - 581 Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 8 p. 901 - 905

~%

H-Pro-NHME.HCL Structure

H-Pro-NHME.HCL

CAS#:33208-98-9

Literature: Yonezawa; Jingu; Katakai Synthetic Communications, 1994 , vol. 24, # 9 p. 1239 - 1246

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(S)-pyrrolidine-2-(N-methyl)carboxamide hydrochloride
(S)-N-Methyl-2-pyrrolidinecarboxamide HCl
2-Pyrrolidinecarboxamide, N-methyl-, (2S)-, hydrochloride (1:1)
L-PROLINE-METHYLAMIDE HYDROCHLORIDE
N-Methyl-L-prolinamide hydrochloride (1:1)
H-L-Pro-NHNe hydrochloride
H-PRO-NHCH3 HCL
H-PRO-NHME HCL
L-prolyl-N'-methylamide hydrochloride
N-Methylamide-L-proline hydrochloride
(S)-N-methylpyrrolidine-2-carboxamide hydrochloride
ProNHMe*HCl
pyrrolidine-2-carboxylic acid methylamide hydrochloride
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