AG-13958

Modify Date: 2024-04-05 16:39:13

AG-13958 structure	Common Name	AG-13958
	CAS Number	319460-94-1	Molecular Weight	467.498
	Density	1.4±0.1 g/cm3	Boiling Point	648.4±55.0 °C at 760 mmHg
	Molecular Formula	C₂₆H₂₂FN₇O	Melting Point	N/A
	MSDS	N/A	Flash Point	345.9±31.5 °C

Use of AG-13958

AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD)[1].

Name	N-[2-Fluoro-5-({3-[(E)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}amin o)phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide
Synonym	More Synonyms

Description	AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD)[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	VEGFR
References	[1]. M.B. Kosa, et al. Ocular and Systemic Pharmacokinetics of AG-013958 With Sub-Tenon Administration To Cynomologus Monkeys. Investigative Ophthalmology & Visual Science May 2005, Vol.46, 5379.

Density	1.4±0.1 g/cm3
Boiling Point	648.4±55.0 °C at 760 mmHg
Molecular Formula	C₂₆H₂₂FN₇O
Molecular Weight	467.498
Flash Point	345.9±31.5 °C
Exact Mass	467.186981
PSA	100.52000
LogP	3.35
Vapour Pressure	0.0±1.9 mmHg at 25°C
Index of Refraction	1.691

N-[2-Fluoro-5-({3-[(E)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}amino)phenyl]-1,4-dimethyl-1H-pyrazole-5-carboxamide

2,5-dimethyl-2H-pyrazole-3-carboxylic acid {2-fluoro-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylamino]-phenyl}-amide

1H-Pyrazole-5-carboxamide, N-[2-fluoro-5-[[3-[(E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]amino]phenyl]-1,3-dimethyl-

6-[N-(3-((1,3-dimethyl-1H-pyrazol-5-yl)carboxamido)-4-fluoro-phenyl)amino]-3-(E)-[2-(pyridin-2-yl)ethenyl]-1H-indazole

N-[2-Fluoro-5-({3-[(E)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}amino)phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide

6-[methyl(phenylsulfonyl)amino]-hexanoic acid

1H-Pyrazole-5-carboxamide, N-[2-fluoro-5-[[3-[(E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]amino]phenyl]-1,4-dimethyl-

6-(benzenesulfonyl-methyl-amino)-hexanoic acid

6-(Methyl(phenylsulphonyl)amino)hexanoic acid

6-(Benzolsulfonyl-methyl-amino)-hexansaeure

DC Chemicals Limited
China
Product Name: AG13958
Price: $750.0/100mg $1200.0/250mg $2600.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-[2-Fluoro-5-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]amino]phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Price: ￥4675/10 mM * 1 mL in DMSO

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AG-13958

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