Isoxazole

Modify Date: 2024-01-02 09:43:56

Isoxazole Structure
Isoxazole structure
Common Name Isoxazole
CAS Number 288-14-2 Molecular Weight 69.062
Density 1.1±0.1 g/cm3 Boiling Point 95.5±9.0 °C at 760 mmHg
Molecular Formula C3H3NO Melting Point N/A
MSDS N/A Flash Point 8.9±0.0 °C

 Use of Isoxazole


Isoxazole is a drug scaffold that can be used to develop new drugs with various biological activities (e.g. anti-microbial, anti-viral, anti-cancer, anti-inflammatory, immunomodulatory, anti-convulsant or anti-diabetic properties)[1][2].

 Names

Name isoxazole
Synonym More Synonyms

 Isoxazole Biological Activity

Description Isoxazole is a drug scaffold that can be used to develop new drugs with various biological activities (e.g. anti-microbial, anti-viral, anti-cancer, anti-inflammatory, immunomodulatory, anti-convulsant or anti-diabetic properties)[1][2].
Related Catalog
References

[1]. Zhu J, et al. The recent progress of isoxazole in medicinal chemistry. Bioorg Med Chem. 2018 Jul 23;26(12):3065-3075.

[2]. Sysak A, et al. Isoxazole ring as a useful scaffold in a search for new therapeutic agents. Eur J Med Chem. 2017 Sep 8;137:292-309.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 95.5±9.0 °C at 760 mmHg
Molecular Formula C3H3NO
Molecular Weight 69.062
Flash Point 8.9±0.0 °C
Exact Mass 69.021461
PSA 26.03000
LogP 0.08
Vapour density 2.4 (vs air)
Vapour Pressure 51.7±0.2 mmHg at 25°C
Index of Refraction 1.422
Storage condition Store at RT.

 Safety Information

Hazard Codes F:Flammable;
Risk Phrases R11
Safety Phrases S16-S23/33
RIDADR UN 1993 3/PG 2
WGK Germany 3
Packaging Group II
Hazard Class 3
HS Code 29349990

 Synthetic Route

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

EINECS 206-018-7
1-Oxa-2-azacyclopentadiene
Isoxazole
Isoxazoles
1,2-Oxazole
Isooxazole
MFCD00003149
Isoxazol
isoxazole acid
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