5'-chloro-2'-hydroxy-4'-methylacetophenone

Modify Date: 2024-01-02 20:20:45

5'-chloro-2'-hydroxy-4'-methylacetophenone Structure
5'-chloro-2'-hydroxy-4'-methylacetophenone structure
Common Name 5'-chloro-2'-hydroxy-4'-methylacetophenone
CAS Number 28480-70-8 Molecular Weight 184.62000
Density 1.25g/cm3 Boiling Point 137 °C / 15mmHg
Molecular Formula C9H9ClO2 Melting Point 70-73 °C(lit.)
MSDS Chinese USA Flash Point 132.2ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 1-(5-chloro-2-hydroxy-4-methylphenyl)ethanone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.25g/cm3
Boiling Point 137 °C / 15mmHg
Melting Point 70-73 °C(lit.)
Molecular Formula C9H9ClO2
Molecular Weight 184.62000
Flash Point 132.2ºC
Exact Mass 184.02900
PSA 37.30000
LogP 2.55660
Vapour Pressure 0.000889mmHg at 25°C
Index of Refraction 1.562

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2914700090

 Synthetic Route

~19%

5'-chloro-2'-hydroxy-4'-methylacetophenone Structure

5'-chloro-2'-hy...

CAS#:28480-70-8

Literature: Akamanchi; Padmawar; Thatte; Rege; Dahanukar Pharmacy and Pharmacology Communications, 1999 , vol. 5, # 5 p. 323 - 329

~75%

5'-chloro-2'-hydroxy-4'-methylacetophenone Structure

5'-chloro-2'-hy...

CAS#:28480-70-8

Literature: Jadhav, Vidyadhar K.; Deshmukh, Anjali P.; Wadagaonkar, Prakash P.; Salunkhe, Manikrao M. Synthetic Communications, 2000 , vol. 30, # 8 p. 1521 - 1527

~%

5'-chloro-2'-hydroxy-4'-methylacetophenone Structure

5'-chloro-2'-hy...

CAS#:28480-70-8

Literature: Nittoli, Thomas; Curran, Kevin; Insaf, Shabana; DiGrandi, Martin; Orlowski, Mark; Chopra, Rajiv; Agarwal, Atul; Howe, Anita Y. M.; Prashad, Amar; Floyd, M. Brawner; Johnson, Bernard; Sutherland, Alan; Wheless, Karen; Feld, Boris; O'Connell, John; Mansour, Tarek S.; Bloom, Jonathan Journal of Medicinal Chemistry, 2007 , vol. 50, # 9 p. 2108 - 2116

~%

5'-chloro-2'-hydroxy-4'-methylacetophenone Structure

5'-chloro-2'-hy...

CAS#:28480-70-8

Literature: Kelode; Mandlik; Aswar Oriental Journal of Chemistry, 2011 , vol. 27, # 3 p. 1053 - 1062

~%

5'-chloro-2'-hydroxy-4'-methylacetophenone Structure

5'-chloro-2'-hy...

CAS#:28480-70-8

Literature: Kindler; Oelschlaeger Chemische Berichte, 1954 , vol. 87, p. 194,201

~%

5'-chloro-2'-hydroxy-4'-methylacetophenone Structure

5'-chloro-2'-hy...

CAS#:28480-70-8

Literature: Royer et al. Bulletin de la Societe Chimique de France, 1957 , p. 1379,1386

 Customs

HS Code 2914700090
Summary HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

 Articles3

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A Highly Sensitive and Selective Spectrophotometric Determination of Vanadium (V) Using 6-Chloro-3-hydroxy-7-methyl-2-(2-thienyl)-4H-chromen-4-one. Agnihotri N, et al.

Anal. Sci. 15(12) , 1261-64, (1999)

Pyridinium iodochloride: An efficient reagent for iodination of hydroxylated aromatic ketones and aldehydes. Khansole SV, et al.

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 Synonyms

2-Acetyl-4-chloro-5-methylphenol
2-hydroxy-4-methyl-5-chloroacetophenone
MFCD00191920
2-hydroxy-5-chloro-4-methylacetophenone
4-Acetyl-2-chloro-5-hydroxytoluene
4-methyl-5-chloro-2-hydroxyacetophenone
5'-Chloro-2'-hydroxy-4'-methylacetophenone
5-chloro-4-methyl-2-hydroxyacetophenone