Robenidine hydrochloride

Modify Date: 2024-01-06 20:21:53

Robenidine hydrochloride Structure
Robenidine hydrochloride structure
Common Name Robenidine hydrochloride
CAS Number 25875-51-8 Molecular Weight 334.20
Density 1.33 g/cm3 Boiling Point 488.1ºC at 760 mmHg
Molecular Formula C15H13Cl2N5 Melting Point N/A
MSDS N/A Flash Point 249ºC

 Use of Robenidine hydrochloride


Robenidine is a coccidiostat agent that can be used for the research of coccidiosis caused by parasites in the Eimeria genus[1].

 Names

Name 1,2-bis[(E)-(4-chlorophenyl)methylideneamino]guanidine
Synonym More Synonyms

 Robenidine hydrochloride Biological Activity

Description Robenidine is a coccidiostat agent that can be used for the research of coccidiosis caused by parasites in the Eimeria genus[1].
Related Catalog
References

[1]. Krollenbrock A, et, al. Robenidine Analogues Are Potent Antimalarials in Drug-Resistant Plasmodium falciparum. ACS Infect Dis. 2021 Jul 9;7(7):1956-1968.  

 Chemical & Physical Properties

Density 1.33 g/cm3
Boiling Point 488.1ºC at 760 mmHg
Molecular Formula C15H13Cl2N5
Molecular Weight 334.20
Flash Point 249ºC
Exact Mass 333.05500
PSA 72.63000
LogP 4.35690
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.634

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ME8650000
CHEMICAL NAME :
Guanidine, 1,3-bis((p-chlorobenzylidene)amino)-
CAS REGISTRY NUMBER :
25875-51-8
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C15-H13-Cl2-N5
MOLECULAR WEIGHT :
334.23
WISWESSER LINE NOTATION :
GR D1 UNMYUM&MNU1R DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 57(9),53,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1212 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 53(11),69,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1245 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 57(9),53,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 57(9),53,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
1017 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 57(9),53,1981

 Synonyms

Khimcoccid
Chimcoccide
Khimkoktsid
Robenidine
Khimkoktside
Robenidine hydrochloride
EINECS 247-308-3