Robenidine hydrochloride

Names

[ Name ]:
Robenidine hydrochloride

[Synonym ]:
Khimcoccid
Chimcoccide
Khimkoktsid
Robenidine
Khimkoktside
Robenidine hydrochloride
EINECS 247-308-3

Biological Activity

[Description]:

Robenidine is a coccidiostat agent that can be used for the research of coccidiosis caused by parasites in the Eimeria genus[1].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. Krollenbrock A, et, al. Robenidine Analogues Are Potent Antimalarials in Drug-Resistant Plasmodium falciparum. ACS Infect Dis. 2021 Jul 9;7(7):1956-1968.

Chemical & Physical Properties

[ Density]:
1.33 g/cm3

[ Boiling Point ]:
488.1ºC at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₃Cl₂N₅

[ Molecular Weight ]:
334.20

[ Flash Point ]:
249ºC

[ Exact Mass ]:
333.05500

[ PSA ]:
72.63000

[ LogP ]:
4.35690

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.634

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ME8650000

CHEMICAL NAME :: Guanidine, 1,3-bis((p-chlorobenzylidene)amino)-

CAS REGISTRY NUMBER :: 25875-51-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C15-H13-Cl2-N5

MOLECULAR WEIGHT :: 334.23

WISWESSER LINE NOTATION :: GR D1 UNMYUM&MNU1R DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 57(9),53,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1212 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 53(11),69,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1245 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 57(9),53,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 57(9),53,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: 1017 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 57(9),53,1981

Synthetic Route

Click to get detail synthetic route

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.