3'-Chloro-3'-deoxythymidine

Modify Date: 2024-01-10 21:39:39

3'-Chloro-3'-deoxythymidine Structure
3'-Chloro-3'-deoxythymidine structure
Common Name 3'-Chloro-3'-deoxythymidine
CAS Number 25526-94-7 Molecular Weight 260.67
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C10H13ClN2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3'-Chloro-3'-deoxythymidine


3′-Chloro-3′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 3'-Desoxy-3'-chlor-thymidin
Synonym More Synonyms

 3'-Chloro-3'-deoxythymidine Biological Activity

Description 3′-Chloro-3′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C10H13ClN2O4
Molecular Weight 260.67
Exact Mass 260.056396
PSA 84.32000
LogP -0.63
Index of Refraction 1.598

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

3'-Chloro-3'-deoxythymidine (Zidovudine Related Compound B)
Zidovudine Related Compound B
3'-Chloro-3'-deoxythymidine
Thymidine, 3'-chloro-3'-deoxy-