2-Palmitoylglycerol

Modify Date: 2024-01-02 13:39:51

2-Palmitoylglycerol structure	Common Name	2-Palmitoylglycerol
	CAS Number	23470-00-0	Molecular Weight	330.50300
	Density	0.969g/cm3	Boiling Point	460.6ºC at 760mmHg
	Molecular Formula	C₁₉H₃₈O₄	Melting Point	68-70°C
	MSDS	USA	Flash Point	150.8ºC

Use of 2-Palmitoylglycerol

2-Palmitoylglycerol (2-Palm-Gl), an congener of 2-arachidonoylglycerol (2-AG), is a modest cannabinoid receptor CB1 agonist. 2-Palmitoylglycerol also may be an endogenous ligand for GPR119[1].

Name	2-Palmitoyl-rac-glycerol
Synonym	More Synonyms

Description	2-Palmitoylglycerol (2-Palm-Gl), an congener of 2-arachidonoylglycerol (2-AG), is a modest cannabinoid receptor CB1 agonist. 2-Palmitoylglycerol also may be an endogenous ligand for GPR119[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor
Target	CB1
In Vitro	2-Palmitoylglycerol (2-PG) modestly internalizes CB1 receptor on its own at concentrations as low as 300nM. 2-Palmitoylglycerol behaves as a very modest antagonist in depolarization-induced suppression of excitation (DSE)[1].
References	[1]. Natalia Murataeva, et al. Where's my entourage? The curious case of 2-oleoylglycerol, 2-linolenoylglycerol, and 2-palmitoylglycerol. Pharmacol Res. 2016 Aug;110:173-180.

Density	0.969g/cm3
Boiling Point	460.6ºC at 760mmHg
Melting Point	68-70°C
Molecular Formula	C₁₉H₃₈O₄
Molecular Weight	330.50300
Flash Point	150.8ºC
Exact Mass	330.27700
PSA	66.76000
LogP	4.36410
Index of Refraction	1.4434 (estimate)
Storage condition	−20°C

Hazard Codes	Xi
Risk Phrases	43
Safety Phrases	36/37
RIDADR	NONH for all modes of transport
HS Code	2915709000

(2-phenyl-1,3-d...

CAS#:56599-87-2

~96%

2-Palmitoylglycerol

CAS#:23470-00-0

Literature: Kim, Young-Ah; Park, Myoung-Soon; Kim, Young Hwan; Han, So-Yeop Tetrahedron, 2003 , vol. 59, # 16 p. 2921 - 2928

2-(palmitoyloxy...

CAS#:101036-66-2

~79%

2-Palmitoylglycerol

CAS#:23470-00-0

Literature: Whitten, Kyle M.; Makriyannis, Alexandros; Vadivel, Subramanian K. Tetrahedron, 2012 , vol. 68, # 27-28 p. 5422 - 5428

Palmitic acid

CAS#:57-10-3

Glycerol

CAS#:56-81-5

~49%

2-Palmitoylglycerol

CAS#:23470-00-0

Literature: Han; Cho; Kim; Seo; Moon; Jhon Bioorganic and medicinal chemistry letters, 1999 , vol. 9, # 1 p. 59 - 64

Tripalmitin

CAS#:555-44-2

~95%

2-Palmitoylglycerol

CAS#:23470-00-0

Literature: Schmid; Bornscheuer; Soumanou; McNeill JAOCS, Journal of the American Oil Chemists' Society, 1998 , vol. 75, # 11 p. 1527 - 1531

Methyl palmitate

CAS#:112-39-0

Glycerol

CAS#:56-81-5

N/A

CAS#:305847-08-9

1,2-Dipalmitoyl...

CAS#:1042289-75-7

Detail

Literature: Kharchafi, Ghizlane; Jerome, Francois; Adam, Isabelle; Pouilloux, Yannick; Barrault, Joel New Journal of Chemistry, 2005 , vol. 29, # 7 p. 928 - 934

Triethyl borate

CAS#:150-46-9

metaboric acid

CAS#:13460-50-9

Hexadecanoic ac...

CAS#:10588-87-1

2-Palmitoylglycerol

CAS#:23470-00-0

Literature: Martin Journal of the American Chemical Society, 1953 , vol. 75, p. 5482

N/A

CAS#:305847-08-9

2-Palmitoylglycerol

CAS#:23470-00-0

Literature: Boswinkel; Derksen; Van't Riet; Cuperus JAOCS, Journal of the American Oil Chemists' Society, 1996 , vol. 73, # 6 p. 707 - 711

Precursor 9
CAS#:56599-87-2 (2-phenyl-1,3-d... CAS#:101036-66-2 2-(palmitoyloxy... CAS#:57-10-3 Palmitic acid CAS#:56-81-5 Glycerol
CAS#:555-44-2 Tripalmitin CAS#:112-39-0 Methyl palmitate CAS#:150-46-9 Triethyl borate CAS#:13460-50-9 metaboric acid
CAS#:10588-87-1 Hexadecanoic ac...
DownStream 5
CAS#:142-91-6 Isopropyl palmitate CAS#:3331-34-8 1-Oleoyl-2-Palm... CAS#:1716-07-0 1,3-Dioleoyl-2-... CAS#:1487-51-0 1-Palmitoyl-3-O...
CAS#:22128-35-4 1-O-benzyl-2-O-...