PI3Kα-IN-4h

Modify Date: 2024-04-02 21:04:47

PI3Kα-IN-4h structure	Common Name	PI3Kα-IN-4h
	CAS Number	2100855-80-7	Molecular Weight	483.532
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₅N₇O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PI3Kα-IN-4h

PI3Kα-IN-1 is a potent, selective, ATP-competitive dual PI3Kα/mTOR inhibitor with IC50 of 0.5/104 nM respectively; displays good selectivity for PI3Kα; demonstrates cytotoxicity in MCF7 cells, reasonable toxicity in MDA-MB-468 cells, good therapeutic index compared to normal skin fibroblasts, and acceptable in vitro ADME properties.

Name	PI3Kα-IN-4h

Description	PI3Kα-IN-1 is a potent, selective, ATP-competitive dual PI3Kα/mTOR inhibitor with IC50 of 0.5/104 nM respectively; displays good selectivity for PI3Kα; demonstrates cytotoxicity in MCF7 cells, reasonable toxicity in MDA-MB-468 cells, good therapeutic index compared to normal skin fibroblasts, and acceptable in vitro ADME properties.
References	References 1. Al-Ashmawy AAK, et al. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3117-3122. View Related Products by Target PI3K

Molecular Formula	C₂₆H₂₅N₇O₃
Molecular Weight	483.532

DC Chemicals Limited
China
Product Name: PI3Kα-IN-4h
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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