Lauric acid

Modify Date: 2024-01-02 12:11:17

Lauric acid structure	Common Name	Lauric acid
	CAS Number	143-07-7	Molecular Weight	200.318
	Density	0.9±0.1 g/cm3	Boiling Point	296.1±3.0 °C at 760 mmHg
	Molecular Formula	C₁₂H₂₄O₂	Melting Point	44-46 °C(lit.)
	MSDS	Chinese USA	Flash Point	134.1±11.9 °C
	Symbol	GHS05	Signal Word	Danger

Use of Lauric acid

Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.

Name	dodecanoic acid
Synonym	More Synonyms

Description	Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Natural Products >> Acids and Aldehydes Research Areas >> Infection
Target	Human Endogenous Metabolite
References	[1]. Nakatsuji T, et al. Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. J Invest Dermatol. 2009 Oct;129(10):2480-8.

Density	0.9±0.1 g/cm3
Boiling Point	296.1±3.0 °C at 760 mmHg
Melting Point	44-46 °C(lit.)
Molecular Formula	C₁₂H₂₄O₂
Molecular Weight	200.318
Flash Point	134.1±11.9 °C
Exact Mass	200.177628
PSA	37.30000
LogP	5.03
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.448
Stability	Stable. Combustible. Incompatible with bases, oxidizing agents, reducing agents.
Water Solubility	insoluble

Lauric acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OE9800000

CHEMICAL NAME :: Lauric acid

CAS REGISTRY NUMBER :: 143-07-7

BEILSTEIN REFERENCE NO. :: 1099477

LAST UPDATED :: 199701

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C12-H24-O2

MOLECULAR WEIGHT :: 200.36

WISWESSER LINE NOTATION :: QV11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 12 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 131 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 333 gm/kg/13W-C

TOXIC EFFECTS :: Behavioral - food intake (animal) Behavioral - fluid intake

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 108 gm/kg/15W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Yeast - Saccharomyces cerevisiae

DOSE/DURATION :: 10 mg/L

REFERENCE :: NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 294,263,1981 *** REVIEWS *** TOXICOLOGY REVIEW AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 21,100,1960 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84696 No. of Facilities: 1256 (estimated) No. of Industries: 14 No. of Occupations: 34 No. of Employees: 14960 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84696 No. of Facilities: 4690 (estimated) No. of Industries: 51 No. of Occupations: 50 No. of Employees: 77970 (estimated) No. of Female Employees: 17300 (estimated)

Symbol	GHS05
Signal Word	Danger
Hazard Statements	H318
Precautionary Statements	P280-P305 + P351 + P338 + P310
Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi:Irritant
Risk Phrases	R36/38
Safety Phrases	S37/39-S26
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	OE9800000
HS Code	2916399090

Precursor 8
CAS#:112-53-8 1-Dodecanol CAS#:1321499-06-2 3-oxo-2-phenyls... CAS#:112-54-9 Lauryl aldehyde CAS#:108-98-5 Thiophenol
CAS#:288854-03-5 (1R,5R)-1-dodec... CAS#:111-82-0 Methyl laurate CAS#:2437-56-1 1-Tridecene CAS#:71071-51-7 2,2,2-TRICHLORO...
DownStream 10
CAS#:106-13-8 Dodecanoic acid... CAS#:10443-61-5 1H-Imidazole,4,... CAS#:111-56-8 Dodecanoic acid... CAS#:32459-66-8 11-HYDROXY LAUR...
CAS#:4228-00-6 Phenyl dodecanoate CAS#:3775-51-7 Lauroyliminodia... CAS#:3352-87-2 N,N-Diethyldode... CAS#:307-55-1 perfluorolauric acid
CAS#:3397-65-7 L-Glutamic acid... CAS#:4282-44-4 1-Iodoundecane

HS Code	2915900090
Summary	2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin.

AAPS J. 16(4) , 875-83, (2014)

The effect of food intake on the release and degradation of peptide drugs from solid lipid particles is unknown and was therefore investigated in vitro using different fed state media in a lipolysis m...

Combined effects of nutrients and temperature on the production of fermentative aromas by Saccharomyces cerevisiae during wine fermentation.

Appl. Microbiol. Biotechnol. 99(5) , 2291-304, (2015)

Volatile compounds produced by yeast during fermentation greatly influence the organoleptic qualities of wine. We developed a model to predict the combined effects of initial nitrogen and phytosterol ...

Abiogenic Syntheses of Lipoamino Acids and Lipopeptides and their Prebiotic Significance.

Orig. Life Evol. Biosph. 45 , 427-37, (2015)

Researchers have formed peptide bonds under a variety of presumed prebiotic conditions. Here it is proposed that these same conditions would have also formed amide bonds between fatty acids and amino ...

EINECS 205-582-1

Lauric acid

MFCD00002736

Dodecanoic Acid

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Lauric acid
Price: ￥198.0/250mg ￥78.0/500g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Lauric Acid
Price: $150.0/100mg $300.0/250mg $600.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Lauric acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Lauric acid
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Lauric acid
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Lauric acid

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