Lauric acid-13C-1

Modify Date: 2024-01-06 22:11:52

Lauric acid-13C-1 Structure
Lauric acid-13C-1 structure
Common Name Lauric acid-13C-1
CAS Number 287100-78-1 Molecular Weight 201.31
Density N/A Boiling Point 225ºC100 mm Hg(lit.)
Molecular Formula C1113CH24O2 Melting Point 44-46ºC(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of Lauric acid-13C-1


Lauric acid-13C-1 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively[1].

 Names

Name Dodecanoic acid-2-13C
Synonym More Synonyms

 Lauric acid-13C-1 Biological Activity

Description Lauric acid-13C-1 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Nakatsuji T, et al. Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. J Invest Dermatol. 2009 Oct;129(10):2480-8.

 Chemical & Physical Properties

Boiling Point 225ºC100 mm Hg(lit.)
Melting Point 44-46ºC(lit.)
Molecular Formula C1113CH24O2
Molecular Weight 201.31
Exact Mass 201.18100
PSA 37.30000
LogP 3.99190

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
WGK Germany 3

 Synonyms

Lauric acid-2-13C