Levofloxacin hydrate
Modify Date: 2024-01-02 15:39:59
Levofloxacin hydrate structure
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Common Name | Levofloxacin hydrate | ||
|---|---|---|---|---|
| CAS Number | 138199-71-0 | Molecular Weight | 370.38 | |
| Density | 1.48g/cm3 | Boiling Point | 571.5ºC at 760mmHg | |
| Molecular Formula | C18H20FN3O4.0.5H2O | Melting Point | 214-216°C | |
| MSDS | N/A | Flash Point | N/A | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
Use of Levofloxacin hydrateLevofloxacin hydrate is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.Target: AntibacterialLevofloxacin reduced bacterial load compared with placebo by 4.9-fold (95% confidence interval, 1.4-25.7; P=0.02) at day 7 but had no effect at any point on any marker of neutrophilic airway inflammation. In patients with a baseline bacterial load of more than 10(6) cfu/mL, levofloxacin treatment was associated with a 26.5% (95% confidence interval, 1.8%-51.3%; P=0.04) greater reduction in the percentage neutrophil count compared with placebo at day 7 [1]. Levofloxacin was found to significantly improve the clinical and microbiological parameters in CP individuals [2]. A 30-day course of levofloxacin does not significantly improve BK viral load reduction or allograft function when used in addition to overall reduction of immunosuppression [3]. |
| Name | Levofloxacin Hemihydrate |
|---|---|
| Synonym | More Synonyms |
| Description | Levofloxacin hydrate is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.Target: AntibacterialLevofloxacin reduced bacterial load compared with placebo by 4.9-fold (95% confidence interval, 1.4-25.7; P=0.02) at day 7 but had no effect at any point on any marker of neutrophilic airway inflammation. In patients with a baseline bacterial load of more than 10(6) cfu/mL, levofloxacin treatment was associated with a 26.5% (95% confidence interval, 1.8%-51.3%; P=0.04) greater reduction in the percentage neutrophil count compared with placebo at day 7 [1]. Levofloxacin was found to significantly improve the clinical and microbiological parameters in CP individuals [2]. A 30-day course of levofloxacin does not significantly improve BK viral load reduction or allograft function when used in addition to overall reduction of immunosuppression [3]. |
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| Related Catalog | |
| References |
| Density | 1.48g/cm3 |
|---|---|
| Boiling Point | 571.5ºC at 760mmHg |
| Melting Point | 214-216°C |
| Molecular Formula | C18H20FN3O4.0.5H2O |
| Molecular Weight | 370.38 |
| PSA | 84.24000 |
| LogP | 1.48260 |
| Vapour Pressure | 6.7E-14mmHg at 25°C |
| Storage condition | -20°C Freezer |
| Symbol |
GHS07, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H317-H334-H361d-H362 |
| Precautionary Statements | P261-P263-P280-P342 + P311 |
| Hazard Codes | N |
| Risk Phrases | 50/53 |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
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Levofloxacin hydrate CAS#:138199-71-0 |
| Literature: US2003/130507 A1, ; |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
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Evaluation of a dental pulp-derived cell sheet cultured on amniotic membrane substrate.
Biomed Mater Eng 25(2) , 203-12, (2015) Mesenchymal stem cells (MSC) are transplanted for periodontal tissue regeneration, and the periodontal ligament (PDL) is regenerated using a cultured cell sheet. This cultured cell sheet is prepared u... |
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Poly(ADP-Ribose) Polymerase Inhibition Improves Corneal Epithelial Innervation and Wound Healing in Diabetic Rats.
Invest. Ophthalmol. Vis. Sci. 56(3) , 1948-55, (2015) We evaluated the effect of poly(ADP-ribose) polymerase (PARP) inhibition by using 1,5-isoquinolinediol (ISO) on corneal epithelial innervation in diabetic rats.ISO (3 mg/kg, intraperitoneal) or vehicl... |
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Simple and accurate quantitative analysis of 20 anti-tuberculosis drugs in human plasma using liquid chromatography-electrospray ionization-tandem mass spectrometry.
J. Pharm. Biomed. Anal. 102 , 9-16, (2014) A simple and accurate liquid chromatography (LC)-tandem mass spectrometry (MS/MS) method for the quantitation of 20 anti-tuberculosis (anti-TB) drugs in human plasma, was developed as a tool for thera... |
| Levofloxacin |
| 7H-1,4-Oxazino[2,3,4-ij]quinoline-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (3S)-, hydrate (1:1) |
| (3S)-9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrate (1:1) |
| MFCD03265511 |
| Levofloxacin hemihydrate |
| (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid hydrate (2:1) |
| Levofloxacin hydrate |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Levofloxacin hydrate
- Price: ￥298.0/5g
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Levofloxacin hydrate
- Price: $200.0/100mg $400.0/250mg $800.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid hydrate (2:1)
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Levofloxacin Hemihydrate
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
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