Fluorescein Biotin

Modify Date: 2024-01-06 20:45:26

Fluorescein Biotin Structure
Fluorescein Biotin structure
Common Name Fluorescein Biotin
CAS Number 134759-22-1 Molecular Weight 831.01200
Density 1.43 g/cm3 Boiling Point N/A
Molecular Formula C42H50N6O8S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fluorescein Biotin


Fluorescein Biotin is used as an alternative to radioactive biotin for detecting and quantitating biotin-binding sites by either fluorescence or absorbance; the the fluorescence or absorbance of Fluorescein Biotin is quenched, upon binding to avidin or streptavidin.

 Names

Name 5(6)-(Biotinamidohexanoylamido)pentylthioureidylfluorescein
Synonym More Synonyms

 Fluorescein Biotin Biological Activity

Description Fluorescein Biotin is used as an alternative to radioactive biotin for detecting and quantitating biotin-binding sites by either fluorescence or absorbance; the the fluorescence or absorbance of Fluorescein Biotin is quenched, upon binding to avidin or streptavidin.
Related Catalog
References

[1]. Gruber HJ, et al. Accurate titration of avidin and streptavidin with biotin-fluorophore conjugates in complex, colored biofluids. Biochim Biophys Acta. 1998 Jul 23;1381(2):203-12.

 Chemical & Physical Properties

Density 1.43 g/cm3
Molecular Formula C42H50N6O8S2
Molecular Weight 831.01200
Exact Mass 830.31300
PSA 256.77000
LogP 7.54440
Index of Refraction 1.699

 Synonyms

6-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-N-[5-[(3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-yl)carbamothioylamino]pentyl]hexanamide
Fluorescein biotin