Tubulin inhibitor 7
Modify Date: 2024-01-09 10:12:50
Tubulin inhibitor 7 structure
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Common Name | Tubulin inhibitor 7 | ||
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| CAS Number | 1309925-41-4 | Molecular Weight | 358.35 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H14N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Tubulin inhibitor 7Tubulin inhibitor 7 (Compound 33c) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 7 inhibits tubulin polymerization with an IC50 of 0.52 μM. Tubulin inhibitor 7 inhibits K562 cell growth with an IC50 of 11 nM[1]. |
| Name | Tubulin inhibitor 7 |
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| Description | Tubulin inhibitor 7 (Compound 33c) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 7 inhibits tubulin polymerization with an IC50 of 0.52 μM. Tubulin inhibitor 7 inhibits K562 cell growth with an IC50 of 11 nM[1]. |
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| Related Catalog | |
| Target |
IC50: 0.52 μM (tubulin polymerization)[1] |
| In Vitro | Tubulin inhibitor 7 blocks mitosis through an arrest of cells in the G2/M phase, as illustrated in typical histograms[1]. Tubulin inhibitor 7 shows excellent antiproliferative potencies with IC50s of 40, 24, 16, 6, 29, and 16 nM for NCIH460, SKOV3, BT549, 451LU, SW480, and DLD-1 tumor cell lines, recpectively[1]. |
| References |
| Molecular Formula | C21H14N2O4 |
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| Molecular Weight | 358.35 |
| Hazard Codes | Xi |
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