Deacetyldiltiazem-d6 hydrochloride

Modify Date: 2024-02-26 22:16:19

Deacetyldiltiazem-d6 hydrochloride Structure
Deacetyldiltiazem-d6 hydrochloride structure
Common Name Deacetyldiltiazem-d6 hydrochloride
CAS Number 1309283-22-4 Molecular Weight 414.97900
Density N/A Boiling Point N/A
Molecular Formula C20H19ClD6N2O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Deacetyldiltiazem-d6 hydrochloride


Deacetyldiltiazem-d6 (hydrochloride) is the deuterium labeled Deacetyldiltiazem hydrochloride[1].

 Names

Name (2S,3S)-5-(2-{Bis[(2H3)methyl]amino}ethyl)-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one hydrochloride (1:1)

 Deacetyldiltiazem-d6 hydrochloride Biological Activity

Description Deacetyldiltiazem-d6 (hydrochloride) is the deuterium labeled Deacetyldiltiazem hydrochloride[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Molecular Formula C20H19ClD6N2O3S
Molecular Weight 414.97900
Exact Mass 414.16500
PSA 78.31000
LogP 3.66470