2,2'-DICHLOROBIPHENYL

Modify Date: 2024-01-03 11:34:01

2,2'-DICHLOROBIPHENYL Structure
2,2'-DICHLOROBIPHENYL structure
Common Name 2,2'-DICHLOROBIPHENYL
CAS Number 13029-08-8 Molecular Weight 223.09800
Density 1.249g/cm3 Boiling Point 289.1ºC at 760mmHg
Molecular Formula C12H8Cl2 Melting Point 79-80℃ (hexane )
MSDS Chinese USA Flash Point 122.4ºC
Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Warning

 Names

Name 2,2'-Dichlorobiphenyl
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.249g/cm3
Boiling Point 289.1ºC at 760mmHg
Melting Point 79-80℃ (hexane )
Molecular Formula C12H8Cl2
Molecular Weight 223.09800
Flash Point 122.4ºC
Exact Mass 222.00000
LogP 4.66040
Vapour Pressure 0.00389mmHg at 25°C
Index of Refraction 1.594

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DV3900000
CHEMICAL NAME :
Biphenyl, 2,2'-dichloro-
CAS REGISTRY NUMBER :
13029-08-8
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C12-H8-Cl2
MOLECULAR WEIGHT :
223.10

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
150 mg/kg/3D-I
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 33,94,1975
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
25 mg/kg/20D-I
TOXIC EFFECTS :
Immunological Including Allergic - decrease in humoral immune response
REFERENCE :
JEPOEC Journal of Environmental Pathology, Toxicology and Oncology. (Chem-Orbital, POB 134, Park Forest, IL 60466) V.5(4)- 1984- Volume(issue)/page/year: 9,283,1989
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
25 mg/kg/20D-I
TOXIC EFFECTS :
Liver - other changes
REFERENCE :
JEPOEC Journal of Environmental Pathology, Toxicology and Oncology. (Chem-Orbital, POB 134, Park Forest, IL 60466) V.5(4)- 1984- Volume(issue)/page/year: 12,17,1993 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1125 mg/kg
SEX/DURATION :
female 1-3 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 40,249,1978
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1500 mg/kg
SEX/DURATION :
female 1-3 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 40,249,1978
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1125 mg/kg
SEX/DURATION :
female 1-3 day(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - parturition
REFERENCE :
BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 16,33,1976

 Safety Information

Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Warning
Hazard Statements H373-H410
Precautionary Statements P273-P391-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes N: Dangerous for the environment;
Risk Phrases R33
Safety Phrases S35
RIDADR UN 2315
RTECS DV3900000
Packaging Group II

 Synthetic Route

 Articles20

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PLoS ONE 8(1) , e52550, (2013)

The oxidative degradation of biphenyl and polychlorinated biphenyls (PCBs) is initiated in Pandoraea pnomenusa B-356 by biphenyl dioxygenase (BPDO(B356)). BPDO(B356), a heterohexameric (αβ)(3) Rieske ...

Possible molecular targets of halogenated aromatic hydrocarbons in neuronal cells.

Biochem. Biophys. Res. Commun. 280(5) , 1372-7, (2001)

Halogenated aromatic hydrocarbon including polychlorinated biphenyls (PCBs) are persistent and bioaccumulative environmental toxicants. Although health effects associated with exposure to these chemic...

Comparative toxicokinetics of 2,2'- and 4,4'-dichlorobiphenyls in the pond snail Lymnaea stagnalis (L.).

Arch. Environ. Contam. Toxicol. 19(4) , 565-71, (1990)

Pond snails (Lymnaea stagnalis (L.)) were treated with 2,2'-dichlorobiphenyl (DCB) or 4,4'-DCB, to examine the toxicokinetic profile of these compounds. Snails were treated orally with 210 micrograms ...

 Synonyms

1-chloro-2-(2-chlorophenyl)benzene