Tyrphostin AG 30

Modify Date: 2024-01-16 17:43:32

Tyrphostin AG 30 structure	Common Name	Tyrphostin AG 30
	CAS Number	122520-79-0	Molecular Weight	205.16700
	Density	1.559g/cm3	Boiling Point	465.6ºC at 760mmHg
	Molecular Formula	C₁₀H₇NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	235.4ºC

Use of Tyrphostin AG 30

Tyrphostin AG30 (AG30) is a potent protein tyrosine kinases (PTK) inhibitor. Tyrphostin AG30 (AG30) selectively inhibits self renewal induction by c-ErbB, and is able to inhibit activation of STAT5 by c-ErbB in primary erythroblasts[1][2].

Name	(E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic acid
Synonym	More Synonyms

Description	Tyrphostin AG30 (AG30) is a potent protein tyrosine kinases (PTK) inhibitor. Tyrphostin AG30 (AG30) selectively inhibits self renewal induction by c-ErbB, and is able to inhibit activation of STAT5 by c-ErbB in primary erythroblasts[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Volberg T, et al. The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions. EMBO J. 1992 May;11(5):1733-42. [2]. Wessely O, et al. Distinct roles of the receptor tyrosine kinases c-ErbB and c-Kit in regulating the balance between erythroid cell proliferation and differentiation. Cell Growth Differ. 1997 May;8(5):481-93.

Description

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. Volberg T, et al. The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions. EMBO J. 1992 May;11(5):1733-42.

[2]. Wessely O, et al. Distinct roles of the receptor tyrosine kinases c-ErbB and c-Kit in regulating the balance between erythroid cell proliferation and differentiation. Cell Growth Differ. 1997 May;8(5):481-93.

Density	1.559g/cm3
Boiling Point	465.6ºC at 760mmHg
Molecular Formula	C₁₀H₇NO₄
Molecular Weight	205.16700
Flash Point	235.4ºC
Exact Mass	205.03800
PSA	101.55000
LogP	1.08938
Vapour Pressure	1.8E-09mmHg at 25°C
Index of Refraction	1.717

Hazard Codes	Xi

2-(1-thienyl)et...

CAS#:132464-92-7

~68%

Tyrphostin AG 30

CAS#:122520-79-0

Literature: Journal of Pharmaceutical Sciences, , vol. 80, # 5 p. 416 - 418

3,4-Dihydroxybe...

CAS#:139-85-5

Tyrphostin AG 30

CAS#:122520-79-0

Literature: Journal of Medicinal Chemistry, , vol. 32, # 10 p. 2344 - 2352

Cyanoacetic acid

CAS#:372-09-8

3,4-Dihydroxybe...

CAS#:139-85-5

Tyrphostin AG 30

CAS#:122520-79-0

Literature: Journal of Medicinal Chemistry, , vol. 34, # 4 p. 1503 - 1505

Precursor 3
CAS#:132464-92-7 2-(1-thienyl)et... CAS#:139-85-5 3,4-Dihydroxybe... CAS#:372-09-8 Cyanoacetic acid
DownStream 0

3.4-Dioxy-benzylidencyanessigsaeure

2-cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid

(E)-2-cyano-3-(3,4-dihydroxyphenyl)acrylic acid

AG 30

2-Propenoic acid,2-cyano-3-(3,4-dihydroxyphenyl)-,(E)

Tyrphostin AG 30

(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenoic acid

Tyrophostin AG 30

2-Cyan-3-(3,4-dihydroxy-phenyl)-acrylsaeure

DC Chemicals Limited
China
Product Name: AG 30
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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Price: ￥564/10 mM * 1 mL in DMSO

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Tyrphostin AG 30

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