SR-33805 structure
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Common Name | SR-33805 | ||
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CAS Number | 121346-32-5 | Molecular Weight | 654.77000 | |
Density | N/A | Boiling Point | 728.7ºC at 760 mmHg | |
Molecular Formula | C34H42N2O9S | Melting Point | N/A | |
MSDS | N/A | Flash Point | 394.5ºC |
Use of SR-33805SR-33805 is a calcium channel antagonist potentially for the treatment of atherosclerosis and heart failure. SR-33805 restored the MI-altered cell shortening without affecting the Ca(2+) transient amplitude, suggesting an increase of myofilament Ca(2+) sensitivity in MI myocytes. A SR33805-induced sensitization of myofilament activation was found to be associated with a slight increase in myosin light chain-2 phosphorylation and a more significant decrease on troponin I (TnI) phosphorylation. Decreased TnI phosphorylation was related to inhibition of protein kinase A activity by SR-33805. |
Name | SR 33805 oxalate,3,4-Dimethoxy-N-methyl-N-[3-[4-[[1-methyl-3-(1-methylethyl)-1H-indol-2-yl]sulfonyl]phenoxy]propyl]benzeneethanamine |
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Boiling Point | 728.7ºC at 760 mmHg |
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Molecular Formula | C34H42N2O9S |
Molecular Weight | 654.77000 |
Flash Point | 394.5ºC |
Exact Mass | 654.26100 |
PSA | 152.98000 |
LogP | 6.33150 |
Vapour Pressure | 4.34E-21mmHg at 25°C |
Hazard Codes | Xi |
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