1816294-67-3
1816294-67-3 structure
- Name: SR-4370
- Chemical Name: SR-4370
- CAS Number: 1816294-67-3
- Molecular Formula: C17H18F2N2O
- Molecular Weight: 304.33
- Catalog: Research Areas Cancer
- Create Date: 2018-04-17 19:29:17
- Modify Date: 2024-01-19 13:06:59
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SR-4370 is an inhibitor of HDAC, with IC50s of 0.13 μM, 0.58 μM, 0.006 μM, 2.3 μM, and 3.4 μM for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively.
| Name | SR-4370 |
|---|
| Description | SR-4370 is an inhibitor of HDAC, with IC50s of 0.13 μM, 0.58 μM, 0.006 μM, 2.3 μM, and 3.4 μM for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively. |
|---|---|
| Related Catalog | |
| Target |
HDAC3:6 nM (IC50) HDAC1:130 nM (IC50) HDAC2:580 nM (IC50) HDAC8:2300 nM (IC50) HDAC6:3400 nM (IC50) |
| In Vitro | SR-4370 is an inhibitor of HDAC, with IC50s of 0.13 μM, 0.58 μM, 0.006 μM, 2.3 μM, and 3.4 μM for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively. SR-4370 is cytotoxic to the breast cancer cells (MDA-MB-231), with an IC50 of 12.6 μM[1]. |
| References |
[1]. LIAO, Daiqing, et al. HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT. WO 2015153516 A1. |
| Molecular Formula | C17H18F2N2O |
|---|---|
| Molecular Weight | 304.33 |
| Storage condition | 2-8℃ |