HE-2500

Modify Date: 2024-01-16 10:03:33

HE-2500 structure	Common Name	HE-2500
	CAS Number	112859-71-9	Molecular Weight	290.42
	Density	1.09g/cm3	Boiling Point	382.5ºC at 760mmHg
	Molecular Formula	C₁₉H₂₇FO	Melting Point	N/A
	MSDS	N/A	Flash Point	207.3ºC

Use of HE-2500

Fluasterone is a potent G6PD inhibitor with a Ki of 0.51 μM. Fluasterone has anti-inflammatory, cancer preventive, and anti-diabetic effects. Fluasterone is orally active[1][2][3].

Name	Fluasterone
Synonym	More Synonyms

Description	Fluasterone is a potent G6PD inhibitor with a Ki of 0.51 μM. Fluasterone has anti-inflammatory, cancer preventive, and anti-diabetic effects. Fluasterone is orally active[1][2][3].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
Target	Ki: 0.51 μM (G6PD)[3]
In Vivo	Fluasterone (0.2% and 0.3%; in diet for 39 days) 对糖尿病小鼠有抗高血糖作用[2]。 Fluasterone (200 μg/mouse; intradermal injection; once) 抑制 TPA 诱导的急性炎症和表皮增生作用[3]。 Animal Model: Male C57BL/KsJ db/db mice, diabetic model[2] Dosage: 0.2% and 0.3% Administration: In the diet for 39 days Result: Markedly reduced plasma glucose levels.
References	[1]. Schwartz AG, et al. Potential therapeutic use of dehydroepiandrosterone and structural analogs. Diabetes Technol Ther. 2001 Summer;3(2):221-4. [2]. Pashko LL, et al. Antihyperglycemic effect of dehydroepiandrosterone analogue 16 alpha-fluoro-5-androsten-17-one in diabetic mice. Diabetes. 1993 Aug;42(8):1105-8. [3]. Schwartz AG, et al. Suppression of 12-O-tetradecanoylphorbol-13-acetate-induced epidermal hyperplasia and inflammation by the dehydroepiandrosterone analog 16alpha-fluoro-5-androsten-17-one and its reversal by NADPH liposomes. Cancer Lett. 2001 Jul 10;168(1):7-14.

Density	1.09g/cm3
Boiling Point	382.5ºC at 760mmHg
Molecular Formula	C₁₉H₂₇FO
Molecular Weight	290.42
Flash Point	207.3ºC
Exact Mass	290.20500
PSA	17.07000
LogP	4.85640
Vapour Pressure	4.7E-06mmHg at 25°C
Index of Refraction	1.529

16-fluoro-5-androsten-17-one

DC Chemicals Limited
China
Product Name: HE-2500
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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