Nicotinyl alcohol

Modify Date: 2024-01-02 20:09:50

Nicotinyl alcohol Structure
Nicotinyl alcohol structure
Common Name Nicotinyl alcohol
CAS Number 100-55-0 Molecular Weight 109.126
Density 1.1±0.1 g/cm3 Boiling Point 266.0±0.0 °C at 760 mmHg
Molecular Formula C6H7NO Melting Point -7 °C
MSDS Chinese USA Flash Point 97.5±20.4 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Nicotinyl alcohol


3-Pyridinemethanol (Nicotinyl alcohol), a pyridine derivative, is a cholesterol-lowering agent[1][2].

 Names

Name 3-Pyridinemethanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 266.0±0.0 °C at 760 mmHg
Melting Point -7 °C
Molecular Formula C6H7NO
Molecular Weight 109.126
Flash Point 97.5±20.4 °C
Exact Mass 109.052765
PSA 33.12000
LogP -0.46
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.551
Storage condition 2-8°C
Water Solubility soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UT4690000
CHEMICAL NAME :
3-Pyridinemethanol
CAS REGISTRY NUMBER :
100-55-0
BEILSTEIN REFERENCE NO. :
0107851
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C6-H7-N-O
MOLECULAR WEIGHT :
109.14
WISWESSER LINE NOTATION :
T6NJ C1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 11,242,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 22,483,1962

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/38
Safety Phrases S26-S36-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS UT4690000
HS Code 29333999

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles25

More Articles
Inhibitory effects of niacin and its analogues on induction of ornithine decarboxylase activity by diethylnitrosamine in rat liver.

Biochem. Pharmacol. 36(18) , 3015-9, (1987)

Pharmacological doses of niacin and its analogues were given intraperitoneally to rats with and without coadministration of a hepatocarcinogenic dose of diethylnitrosamine (DEN), and their effects on ...

The role of p53 in the cellular toxicity by active trans-platinum complexes containing isopropylamine and hydroxymethylpyridine.

Eur. J. Med. Chem. 45(1) , 134-41, (2010)

Despite some initial research that reported a lack of activity of trans geometry, complexes with general formula trans-[PtCl2(L)(L')] exhibit an important cytotoxic activity in cisplatin-sensitive and...

Oxidation of alcohols using a manganese (II) complex based on a pentakis benzimidazole amide ligand.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 74(2) , 536-43, (2009)

A pentakis benzimidazole based penta-amide ligand diethylenetriamine-N,N,N',N',N''-pentakis(2-methyl benzimidazolyl)penta-amide [GBDTPA] has been synthesized and utilized to prepare Mn (II) complexes ...

 Synonyms

(Pyridin-3-yl)methanol
3-Pyridylmethanol
pyridylcarbinol
pyridin-3-ylmethanol
3-Pyridinylmethanol
b-Pyridinecarbinol
3-PYRIDINYLCARBINOL
3-hydroxymethylpyridine
β-Pyridinecarbinol
3-Pyridinemethanol
pyridine, 3-(hydroxymethyl)-
3-(Hydroxymethyl)pyridine
EINECS 202-864-6
Nicotinyl alcohol
β-Picolyl alcohol
Pyridylmethanol
MFCD00006407
RO 1-5155
b-Pyridylcarbinol
β-Pyridylcarbinol
b-Picolyl Alcohol
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