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103438-88-6

103438-88-6 structure
103438-88-6 structure

Name 2-fluoro-3-methoxybenzaldehyde
Synonyms 2-Fluoro-3-methoxybenzaldehyde
2-Fluoro-3-formylanisole
VHR BF CO1
2-fluoro-methoxy-benzaldehyde
6-formyl-2-methoxyfluorobenzene
MFCD03411962
Benzaldehyde, 2-fluoro-3-methoxy-
2-fluoro-3-methoxy-benzaldehyde
2-Fluoro-m-anisaldehyde
Density 1.2±0.1 g/cm3
Boiling Point 239.9±20.0 °C at 760 mmHg
Melting Point 47-51 °C(lit.)
Molecular Formula C8H7FO2
Molecular Weight 154.138
Flash Point 96.1±16.7 °C
Exact Mass 154.043015
PSA 26.30000
LogP 1.74
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.526
Storage condition Keep Cold
Material Safety Data Sheet

Section1. Identification of the substance
2-Fluoro-3-methoxybenzaldehyde
Product Name:
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H302:Harmful if swallowed
H315:Causes skin irritation
H317:May cause an allergic skin reaction
H318:Causes serious eye damage
May cause respiratory irritation
H335:
P261:Avoid breathing dust/fume/gas/mist/vapours/spray
P280:Wear protective gloves/protective clothing/eye protection/face protection
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing

Section3. Composition/information on ingredients.
2-Fluoro-3-methoxybenzaldehyde
Ingredient name:
CAS number:103438-88-6

Section4. First aid measures
Immediately wash skin with copious amounts of water for at least 15 minutes while removing
Skin contact:
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.
Ingestion:

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels, refrigerated.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Not specified
Appearance:
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula:C8H7FO2
Molecular weight:154.1

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, hydrogen fluoride.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302-H315-H317-H318-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2913000090

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Literature: ELI LILLY AND COMPANY Patent: WO2004/43931 A1, 2004 ; Location in patent: Page 40-41 ; WO 2004/043931 A1

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Literature: SCHERING AKTIENGESELLSCHAFT Patent: WO2005/34939 A1, 2005 ; Location in patent: Page/Page column 67 ;

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103438-88-6

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 14 p. 4599 - 4604

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103438-88-6

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 14 p. 4599 - 4604

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Literature: Journal of Medicinal Chemistry, , vol. 29, # 10 p. 1982 - 1988

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Literature: Journal of Organic Chemistry, , vol. 53, # 14 p. 3145 - 3147
HS Code 2913000090
Summary HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%