- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: teriflunomide
- Price: ￥1148.0/100mg ￥478.0/25mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: A77 1726
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 2-CYANO-3-HYDROXY-N-(4-(TRIFLUOROMETHYL)PHENYL)BUT-2-ENAMIDE
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide,teriflunomide
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
108605-62-5
108605-62-5 structure
- Name: teriflunomide
- Chemical Name: 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide,teriflunomide
- CAS Number: 108605-62-5
- Molecular Formula: C12H9F3N2O2
- Molecular Weight: 270.207
- Catalog: Biochemical Inhibitor Metabolism Dehydrogenase inhibitor
- Create Date: 2018-03-29 08:00:00
- Modify Date: 2024-01-02 14:29:17
-
(E/Z)-Teriflunomide ((E/Z)-A77 1726) is the active metabolite of Leflunomide (HY-B0083). Leflunomide is an immunomodulatory agent that may exert effects by inhibiting the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH). Leflunomide can be used for the research of rheumatoid arthritis (RA)[1].
| Name | 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide,teriflunomide |
|---|---|
| Synonyms |
2-Butenamide (2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]
Butanenitrile, 2-[hydroxy[[4-(trifluoromethyl)phenyl]amino]methylene]-3-oxo-, (2Z)- (2Z)-2-(Hydroxy{[4-(trifluoromethyl)phenyl]amino}methylene)-3-oxobutanenitrile 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide Teriflunomide 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide |
| Description | (E/Z)-Teriflunomide ((E/Z)-A77 1726) is the active metabolite of Leflunomide (HY-B0083). Leflunomide is an immunomodulatory agent that may exert effects by inhibiting the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH). Leflunomide can be used for the research of rheumatoid arthritis (RA)[1]. |
|---|---|
| Related Catalog |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 363.0±42.0 °C at 760 mmHg |
| Molecular Formula | C12H9F3N2O2 |
| Molecular Weight | 270.207 |
| Flash Point | 173.3±27.9 °C |
| Exact Mass | 270.061615 |
| PSA | 73.12000 |
| LogP | 0.71 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.552 |
| Storage condition | +2C to +8C |
