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1476-98-8

1476-98-8 structure
1476-98-8 structure

Name hydroquinidine hydrochloride
Synonyms hydroquinidine,monohydrochloride
Einecs 216-024-1
dihydrochinidinhydrochlorid
(9S)-6'-Methoxy-10,11-dihydrocinchonan-9-ol hydrochloride (1:1)
Hydroquinidine Hydrochloride
Hydroquindine Hydrochloride
Hydroquinidine HCl
TCMDC-125509
MFCD00135598
Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (9S)-, hydrochloride (1:1)
Dihydroquinidine Hydrochloride
Density 1.2g/cm3
Boiling Point 498.4ºC at 760mmHg
Melting Point 277-279ºC(lit.)
Molecular Formula C20H27ClN2O2
Molecular Weight 362.894
Flash Point 255.2ºC
Exact Mass 362.176117
PSA 45.59000
LogP 4.13710
Vapour Pressure 9.92E-12mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MX3018000
CHEMICAL NAME :
Hydroquinidine, monohydrochloride
CAS REGISTRY NUMBER :
1476-98-8
LAST UPDATED :
199312
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C20-H26-N2-O2.Cl-H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
369 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,589,1977
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 52,2797,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
32 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,589,1977
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 52,2797,1992
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases 36
RIDADR UN 1544
RTECS MX3018000
Packaging Group III
Hazard Class 6.1(b)