- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: ethylene glycol bis(2-aminoethyl) ether
- Price: ￥88.0/5g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- Chengdu Pukang Biotechnology Co., Ltd.
- China
- Product Name: ethylene glycol bis(2-aminoethyl) ether
- Price: ￥Inquiry/10kg
- Purity: 95.0%
- Stocking Period: Inquiry
- Contact: Lihua Yang
- DC Chemicals Limited
- China
- Product Name: Amino-PEG2-amine
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 1,8-Diamino-3,6-dioxaoctane
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: 1,8-Diamino-3,6-dioxaoctane
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
929-59-9
929-59-9 structure
- Name: ethylene glycol bis(2-aminoethyl) ether
- Chemical Name: 1,8-Diamino-3,6-dioxaoctane
- CAS Number: 929-59-9
- Molecular Formula: C6H16N2O2
- Molecular Weight: 148.203
- Catalog: Chemical reagent Organic reagent Ether
- Create Date: 2018-12-28 12:46:49
- Modify Date: 2024-01-03 11:31:50
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PROTAC Linker 19 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 19 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
| Name | 1,8-Diamino-3,6-dioxaoctane |
|---|---|
| Synonyms |
2,2′-(ethylenedioxy)bis(ethylamine)
1,8-diaminotriethyleneglycol MFCD00040474 2,2'-[1,2-Ethanediylbis(oxy)]diethanamine 2,2'-[ethane-1,2-diylbis(oxy)]diethanamine 1,2-Bis(2-aminoethoxy)ethane UNII-R41ZT4UF34 Jeffamine® EDR-176 EDR-148 TRIETHYLENEGLYCOLDIAMINE 1,8-Diamino-3,6-dioxaoctane DA-10 Jeffamine(R) EDR-176 2,2'-(Ethylenedioxy)bis(ethylamine) 1,8-diamino-3,6-dioxa-octane 3,6-dioxaoctamethylenediamine Ethanamine, 2,2'-(1,2-ethanediylbis(oxy))bis- 3,6-dioxa-1,8-octanediamine EINECS 213-203-6 Ethanamine, 2,2'-[1,2-ethanediylbis(oxy)]bis- Jeffamine EDR-148 |
| Description | PROTAC Linker 19 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 19 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl/ether |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 241.0±20.0 °C at 760 mmHg |
| Molecular Formula | C6H16N2O2 |
| Molecular Weight | 148.203 |
| Flash Point | 104.3±15.5 °C |
| Exact Mass | 148.121185 |
| PSA | 70.50000 |
| LogP | -1.59 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.460 |
| Symbol |
GHS05, GHS07, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H314-H317-H334 |
| Precautionary Statements | P261-P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | C:Corrosive; |
| Risk Phrases | R22;R34;R42/43 |
| Safety Phrases | S23-S26-S36/37/39-S45 |
| RIDADR | UN 2735 8/PG 2 |
| WGK Germany | 3 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2922199090 |
|
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| Literature: Journal of Heterocyclic Chemistry, , vol. 18, p. 297 - 302 |
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| Literature: Journal of Organic Chemistry, , vol. 46, # 15 p. 3064 - 3070 |
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| Literature: Journal of Organic Chemistry, , vol. 39, p. 1315 - 1316 |
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| Literature: US6399071 B1, ; |
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| Literature: Journal of Heterocyclic Chemistry, , vol. 24, p. 1077 - 1083 |
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| Literature: Journal of Organic Chemistry USSR (English Translation), , vol. 16, p. 1124 - 1129 Zhurnal Organicheskoi Khimii, , vol. 16, # 6 p. 1301 - 1307 |
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| Literature: Journal of Organic Chemistry USSR (English Translation), , vol. 16, p. 1124 - 1129 Zhurnal Organicheskoi Khimii, , vol. 16, # 6 p. 1301 - 1307 |
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| Literature: US2412209 , ; US2357176 , ; |
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| Literature: US2412209 , ; |
| Precursor 8 | |
|---|---|
| DownStream 9 | |
| HS Code | 2922199090 |
|---|---|
| Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |