215307-86-1
215307-86-1 structure
- Name: BMS 753
- Chemical Name: 4-{[(1,1,3,3-Tetramethyl-2-oxo-2,3-dihydro-1H-inden-5-yl)carbonyl ]amino}benzoic acid
- CAS Number: 215307-86-1
- Molecular Formula: C21H21NO4
- Molecular Weight: 351.39600
- Catalog: Signaling Pathways Metabolic Enzyme/Protease RAR/RXR
- Create Date: 2017-03-16 09:37:31
- Modify Date: 2024-01-09 21:45:06
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BMS 753 is an isotype-selective retinoic acid receptor α (RARα) agonist, with a Ki of 2 nM[1].
| Name | 4-{[(1,1,3,3-Tetramethyl-2-oxo-2,3-dihydro-1H-inden-5-yl)carbonyl ]amino}benzoic acid |
|---|---|
| Synonyms |
Pentanoic acid,5-[[bis(diethoxyphosphinyl)methyl]amino]-5-oxo
4-[[(2,3-Dihydro-1,1,3,3-tetramethyl-2-oxo-1H-inden-5-yl)carbonyl]amino] benzoic acid 4-[[(2,3-Dihydro-1,1,3,3-tetramethyl-2-oxo-1H-inden-5-yl)carbonyl]amino]-benzoic acid 4-[(Z)-2-ethoxyvinyl]-2-(methylthio)-5-pyrimidinecarbonitrile 4-[(tetraethylbisphosphonomethyl)carbamoyl]butanoic acid |
| Description | BMS 753 is an isotype-selective retinoic acid receptor α (RARα) agonist, with a Ki of 2 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
RARα |
| In Vitro | BMS 753 results in low levels of RARβ transcripts in WT cells, RARγ-/-, but not activates in RARa-/- cells[1]. |
| References |
| Molecular Formula | C21H21NO4 |
|---|---|
| Molecular Weight | 351.39600 |
| Exact Mass | 351.14700 |
| PSA | 83.47000 |
| LogP | 3.84800 |
