Name | N,N-dimethyl-2-[4-[(Z)-3,3,4,4,4-pentadeuterio-1,2-diphenylbut-1-enyl]phenoxy]ethanamine |
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Synonyms |
(E/Z)-Mammaton-d5
Novaldex-d5 Z-Tamoxifen-d5 Mammaton-d5 (E/Z)-Novaldex-d5 (E/Z)-Tamoxifen-d5 trans-Tamoxifen-d5 Tamoxifen-d5 |
Description | Tamoxifen-d5 (ICI 47699-d5) is a deuterium labeled Tamoxifen. Tamoxifen (ICI 47699) is a selective estrogen receptor modulator (SERM). Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity[1][2]. |
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Related Catalog | |
Target |
Estrogen receptor HSP90 |
References |
[1]. Osborne CK. Tamoxifen in the treatment of breast cancer. N Engl J Med. 1998 Nov 26;339(22):1609-18. |
Density | 1.057g/cm3 |
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Boiling Point | 482.3ºC at 760mmHg |
Molecular Formula | C26H24D5NO |
Molecular Weight | 376.54500 |
Flash Point | 140ºC |
Exact Mass | 376.25600 |
PSA | 12.47000 |
LogP | 5.99610 |
Vapour Pressure | 1.85E-09mmHg at 25°C |
Index of Refraction | 1.582 |