17537-31-4

17537-31-4 structure
17537-31-4 structure
  • Name: 1-Phenyl(2H3)ethanone
  • Chemical Name: 2,2,2-trideuterio-1-phenylethanone
  • CAS Number: 17537-31-4
  • Molecular Formula: C8H5D3O
  • Molecular Weight: 123.167
  • Catalog: Chemical reagent Organic reagent Aromatic ketone
  • Create Date: 2018-09-11 21:51:25
  • Modify Date: 2024-01-02 17:56:09
  • Acetophenone-d3 is the deuterium labeled Acetophenone[1]. Acetophenone is an organic compound with simple structure[2].

Name 2,2,2-trideuterio-1-phenylethanone
Synonyms DE160
Acetophenone-methyl-d3
1-Phenyl(H)ethanone
acetophenone-ss,ss,ss-d3
MFCD00064445
Acetophenone-|A,|A,|A-d3
Ethanone-2,2,2-d, 1-phenyl-
Acetophenone-(methyl-d3)
Description Acetophenone-d3 is the deuterium labeled Acetophenone[1]. Acetophenone is an organic compound with simple structure[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Żymańczyk-Duda E, et al. Reductive capabilities of different cyanobacterial strains towards acetophenone as a model substrate - Prospect of applications for chiral building blocks synthesis. Bioorg Chem. 2019 Feb 25. pii: S0045-2068(18)31467-6.  

Density 1.0±0.1 g/cm3
Boiling Point 202.0±0.0 °C at 760 mmHg
Melting Point 19-20ºC(lit.)
Molecular Formula C8H5D3O
Molecular Weight 123.167
Flash Point 82.2±0.0 °C
Exact Mass 123.076347
PSA 17.07000
LogP 1.66
Vapour Pressure 0.3±0.4 mmHg at 25°C
Index of Refraction 1.512
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302-H318
Precautionary Statements P280-P305 + P351 + P338
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases 26
RIDADR UN 3334
WGK Germany 3