138-55-6
138-55-6 structure
- Name: picrocrocin
- Chemical Name: picrocrocin
- CAS Number: 138-55-6
- Molecular Formula: C16H26O7
- Molecular Weight: 330.37300
- Catalog: Biochemical Chinese herbal medicine ingredients
- Create Date: 2018-04-22 08:00:00
- Modify Date: 2024-01-04 17:10:08
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Picrocrocin, an apocarotenoid found in the flowers of Cochliobolus sativus. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells[1].
| Name | picrocrocin |
|---|---|
| Synonyms |
saffron-bitter
Picrocrocine (4R)-2,6,6-trimethyl-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycyclohexene-1-carbaldehyde |
| Description | Picrocrocin, an apocarotenoid found in the flowers of Cochliobolus sativus. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Picrocrocin exerted growth inhibitory effects on the SK-MEL-2 melanoma cells. The IC50 of picrocrocin against the SK-MEL-2 cells was 20 μM at 24-h incubation. The antiproliferative activity of picrocrocin was due to apoptosis and cell cycle arrest. In addition, picrocrocin enhanced the ROS levels and decreased the MMP levels of SK-MEL-2 cells. Finally, picrocrocin inhibited the JAK/STAT5 signalling pathway in the SK-MEL-2 melanoma cells[1]. |
| References |
| Density | 1.31g/cm3 |
|---|---|
| Boiling Point | 520.4ºC at 760mmHg |
| Melting Point | 196 ºC (ethyl acetate ) |
| Molecular Formula | C16H26O7 |
| Molecular Weight | 330.37300 |
| Flash Point | 187.1ºC |
| Exact Mass | 330.16800 |
| PSA | 116.45000 |
| Vapour Pressure | 5.27E-13mmHg at 25°C |
| Index of Refraction | 1.561 |
| Water Solubility | Sparingly soluble (24 g/L) (25 ºC) |
|
~10%
138-55-6 |
| Literature: Mayer; Santer Helvetica Chimica Acta, 1980 , vol. 63, # 6 p. 1463 - 1466 |
|
~%
138-55-6 |
| Literature: Mayer; Santer Helvetica Chimica Acta, 1980 , vol. 63, # 6 p. 1463 - 1466 |
|
~%
138-55-6 |
| Literature: Mayer; Santer Helvetica Chimica Acta, 1980 , vol. 63, # 6 p. 1463 - 1466 |
|
~%
138-55-6 |
| Literature: Mayer; Santer Helvetica Chimica Acta, 1980 , vol. 63, # 6 p. 1463 - 1466 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |