1139-83-9

1139-83-9 structure

Name: Urolithin B
Chemical Name: 3-hydroxybenzo[c]chromen-6-one
CAS Number: 1139-83-9
Molecular Formula: C₁₃H₈O₃
Molecular Weight: 212.20100
Catalog: Signaling Pathways Epigenetics AMPK
Create Date: 2017-12-02 08:11:37
Modify Date: 2024-01-02 18:32:28
Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects. Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass[1][2].

Name	3-hydroxybenzo[c]chromen-6-one
Synonyms	urolithin-B

Description	Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects. Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass[1][2].
Related Catalog	Signaling Pathways >> Epigenetics >> AMPK Signaling Pathways >> PI3K/Akt/mTOR >> Akt Signaling Pathways >> PI3K/Akt/mTOR >> AMPK Signaling Pathways >> MAPK/ERK Pathway >> ERK Signaling Pathways >> MAPK/ERK Pathway >> JNK Signaling Pathways >> Stem Cell/Wnt >> ERK
References	[1]. Lee G, et al. Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microglia. Phytomedicine. 2019 Mar 1;55:50-57. [2]. Rodriguez J, et al. Urolithin B, a newly identified regulator of skeletal muscle mass. J Cachexia Sarcopenia Muscle. 2017 Aug;8(4):583-597.

HS Code	2914400090

HS Code	2914400090
Summary	2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%