Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (2S)-5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone, 3',5,7-Trihydroxy-4-methoxyflavanone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

69097-99-0

69097-99-0 structure

Name: (Rac)-Hesperetin
Chemical Name: 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one
CAS Number: 69097-99-0
Molecular Formula: C₁₆H₁₄O₆
Molecular Weight: 302.27900
Catalog: analytical chemistry Standard Analytical standard
Create Date: 2018-07-05 08:12:33
Modify Date: 2024-01-05 15:31:20
(Rac)-Hesperetin is the racemate of Hesperetin. Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin induces apoptosis via p38 MAPK activation.

Name	5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydrochromen-4-one
Synonyms	3',5,7-Trihydroxy-4'-methoxyflavanone hesperetine

Description	(Rac)-Hesperetin is the racemate of Hesperetin. Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin induces apoptosis via p38 MAPK activation.
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK Research Areas >> Neurological Disease
References	[1]. Arya A, et al. Bioflavonoid hesperetin overcome bicalutamide induced toxicity by co-delivery in novel SNEDDS formulations: Optimization, in vivo evaluation and uptake mechanism. Mater Sci Eng C Mater Biol Appl. 2017 Feb 1;71:954-964 [2]. Liu D, et al. Inhibitory Effect of Hesperetin and Naringenin on Human UDP-Glucuronosyltransferase Enzymes: Implications for Herb-Drug Interactions. Biol Pharm Bull. 2016;39(12):2052-2059. [3]. Shagirtha K, et al. Neuroprotective efficacy of hesperetin against cadmium induced oxidative stress in the brain of rats. Toxicol Ind Health. 2016 Nov 1. pii: 0748233716665301 [4]. Li Q, et al. Hesperetin Induces Apoptosis in Human Glioblastoma Cells via p38 MAPK Activation. Nutr Cancer. 2019 Jul 11:1-8.

Melting Point	227 - 232 °C
Molecular Formula	C₁₆H₁₄O₆
Molecular Weight	302.27900
Exact Mass	302.07900
PSA	96.22000
LogP	2.51850
Storage condition	2-8°C
Water Solubility	ethanol: soluble50mg/mL, clear to almost clear, colorless to slightly yellow

Risk Phrases	R36/37/38
RIDADR	NONH for all modes of transport