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Product Name: 1H-Purine-6,8-dione,2-amino-7,9-dihydro-
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5614-64-2

5614-64-2 structure

5614-64-2 structure

Name: 8-Hydroxyguanine
Chemical Name: 7,8-dihydro-8-oxoguanine
CAS Number: 5614-64-2
Molecular Formula: C₅H₅N₅O₂
Molecular Weight: 167.12500
Catalog: Research Areas Others
Create Date: 2018-08-16 10:59:44
Modify Date: 2024-01-02 11:54:31
8-Hydroxyguanine is a major pre-mutagenic lesion generated from reactive oxygen species. It causes G-T and A-C substitutions.

Name	7,8-dihydro-8-oxoguanine
Synonyms	8-OH-GUA 7,8-DIHYDRO-8-OXOGUANINE 2-AMINO-6,8-DIHYDROXYPURINE 8-Hydroxy-guanin 8-Oxo-7,8-dihydroguanine 8-OXOGUANINE 2-amino-7,9-dihydro-1H-purine-6,8-dione 2-AMINO-6,8-PURINEDIOL 8-Oxodihydroguanine 2-aminopurine-6,8-diol 8-OXOG 8-HYDROXYGUANINE EINECS 227-035-6

Description	8-Hydroxyguanine is a major pre-mutagenic lesion generated from reactive oxygen species. It causes G-T and A-C substitutions.
Related Catalog	Natural Products >> Others Research Areas >> Others
Target	Human Endogenous Metabolite
References	[1]. Arai T, et al. High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress. Carcinogenesis. 2002 Dec;23(12):2005-10. [2]. Floyd RA, et al. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis. 1990 Sep;11(9):1447-50. [3]. Cheng KC, et al. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions. J Biol Chem. 1992 Jan 5;267(1):166-72.

Density	2.49g/cm3
Boiling Point	327.7ºC at 760 mmHg
Melting Point	>400ºC dec.
Molecular Formula	C₅H₅N₅O₂
Molecular Weight	167.12500
Flash Point	152ºC
Exact Mass	167.04400
PSA	120.94000
Index of Refraction	2.156

Hazard Codes	Xi
Safety Phrases	S24/25
HS Code	2933990090

73-40-5 structure

73-40-5

~%

5614-64-2 structure

5614-64-2

Literature: Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry, , vol. 41, # 10 p. 2096 - 2100

Precursor 1
73-40-5
DownStream 3
3868-31-3 69-93-2 113-00-8

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%