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38862-24-7

38862-24-7 structure
38862-24-7 structure
  • Name: N-acryloxysuccinimide
  • Chemical Name: N-Acryloxysuccinimide
  • CAS Number: 38862-24-7
  • Molecular Formula: C7H7NO4
  • Molecular Weight: 169.135
  • Catalog: Research Areas Others
  • Create Date: 2018-03-04 08:00:00
  • Modify Date: 2024-01-02 19:55:36
  • 2,5-Dioxopyrrolidin-1-yl acrylate (N-Succinimidyl acrylate) is a protein crosslinker. 2,5-Dioxopyrrolidin-1-yl acrylate can react with a monoclonal anti-horseradish peroxidase IgG antibody (anti-HRP) to modify lysine residues[1].

Name N-Acryloxysuccinimide
Synonyms N-SucciniMidyl Acrylate
1-(Acryloyloxy)pyrrolidine-2,5-dione
N-acryloxysuccinimide
N-Acryloyloxysuccinimide
Acrylic Acid N-Succinimidyl Ester
1-(Acryloyloxy)-2,5-pyrrolidinedione
2,5-Pyrrolidinedione, 1-[(1-oxo-2-propen-1-yl)oxy]-
2,5-pyrrolidinedione, 1-[(1-oxo-2-propenyl)oxy]-
2,5-Dioxopyrrolidin-1-yl acrylate
MFCD00078261
1-[(1-Oxo-2-propenyl)oxy]-2,5-pyrrolidinedione
2,5-Pyrrolidinedione, 1-((1-oxo-2-propenyl)oxy)-
Description 2,5-Dioxopyrrolidin-1-yl acrylate (N-Succinimidyl acrylate) is a protein crosslinker. 2,5-Dioxopyrrolidin-1-yl acrylate can react with a monoclonal anti-horseradish peroxidase IgG antibody (anti-HRP) to modify lysine residues[1].
Related Catalog
References

[1]. Okyem S, et, al. High-Affinity Points of Interaction on Antibody Allow Synthesis of Stable and Highly Functional Antibody-Gold Nanoparticle Conjugates. Bioconjug Chem. 2021 Aug 18;32(8):1753-1762.  

Density 1.3±0.1 g/cm3
Boiling Point 251.3±23.0 °C at 760 mmHg
Melting Point 69 °C
Molecular Formula C7H7NO4
Molecular Weight 169.135
Flash Point 105.8±22.6 °C
Exact Mass 169.037506
PSA 63.68000
LogP -1.21
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.520
Storage condition 2-8°C
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H319
Precautionary Statements P305 + P351 + P338
Hazard Codes Xn: Harmful;
Risk Phrases R36/37/38;R40;R48/20/22
Safety Phrases S36
RIDADR NONH for all modes of transport
WGK Germany 2
HS Code 2925190090

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38862-24-7 structure

38862-24-7

Literature: Bergbreiter, David E.; Osburn, Philip L.; Li, Chunmei Organic Letters, 2002 , vol. 4, # 5 p. 737 - 740

~65%

38862-24-7 structure

38862-24-7

Literature: Poechlauer, Peter; Hendel, Wolfram Tetrahedron, 1998 , vol. 54, # 14 p. 3489 - 3494

~75%

38862-24-7 structure

38862-24-7

Literature: Handke, Nadege; Trimaille, Thomas; Luciani, Elsa; Rollet, Marion; Delair, Thierry; Verrier, Bernard; Bertin, Denis; Gigmes, Didier Journal of Polymer Science, Part A: Polymer Chemistry, 2011 , vol. 49, # 6 p. 1341 - 1350

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38862-24-7 structure

38862-24-7

Literature: DSM Chemie Linz GmbH Patent: US5734064 A1, 1998 ;
HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%