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39665-12-8

39665-12-8 structure
39665-12-8 structure

Name L(+)-Lysine monohydrate
Synonyms L-Lysine monohydrate
L-Lysine hydrate
lysine,hydrate
L-LYS H2O
LYS,MONOHYDRATE
EINECS 200-294-2
H-Lys-OH H2O
MFCD00151035
Description L-Lysine hydrate is an essential amino acid. L-Lysine hydrate can be research for vascular calcification (VC) and acute pancreatitis[1][2].
Related Catalog
Target

Microbial Metabolite

Human Endogenous Metabolite

In Vitro L-Lysine hydrate (VSMCs) suppresses plasma iPTH and elevates plasma alanine, proline, plasma arginine, and homo arginine, thereby inhibiting apoptosis of VSMCs and mineral precipitation[1].
In Vivo L-Lysine hydrate (40 μg/kg; p.o.) ameliorates arterial calcification in adenine rats and protects the femora from osteoporotic changes in adenine rats[1]. L-Lysine hydrate (10 and 400 mg/kg; i.g. and p.o.; Male mice) inhibits pancreatic tissue damage[2]. Animal Model: Male mice[2] Dosage: 10 and 400 mg/kg Administration: Intraperitoneal injection and oral administration; for 15 days Result: Inhibited the release of the inflammatory cytokine IL-6 and enhance antioxidant activity.
References

[1]. Shimomura A, et, al. Dietary L-lysine prevents arterial calcification in adenine-induced uremic rats. J Am Soc Nephrol. 2014 Sep;25(9):1954-65.

[2]. Al-Malki AL. Suppression of acute pancreatitis by L-lysine in mice. BMC Complement Altern Med. 2015 Jun 23;15:193.

Boiling Point 400ºC at 760 mmHg
Melting Point 212-214 °C
Molecular Formula C6H16N2O3
Molecular Weight 164.20300
Flash Point 195.7ºC
Exact Mass 164.11600
PSA 98.57000
LogP 0.86360
Water Solubility >1500 g/L (20 ºC)
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS OL5540000
HS Code 2922411000
HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%