Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 1,12-Diaminododecane
Price: ￥288.0/25g ￥98.0/5g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: N12N
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,12-Dodecanediamine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

2783-17-7

2783-17-7 structure

Name: 1,12-Diaminododecane
Chemical Name: dodecane-1,12-diamine
CAS Number: 2783-17-7
Molecular Formula: C₁₂H₂₈N₂
Molecular Weight: 200.364
Catalog: Chemical reagent Organic reagent Polyamine
Create Date: 2018-07-14 15:29:23
Modify Date: 2024-01-02 13:30:59
N12N is a polyamine inverse agonist of NMDA receptor.

Name	dodecane-1,12-diamine
Synonyms	1,12-dodecadiamine 1,12-DODECANEDIAME Diaminododecane 1,12-diaminododecyl DODECANEDIAMINE 1,12-dodecamethylenediamine RARECHEM AL BW 0116 Dodecamethylendiamin dodecane-1,12-diamine dodecyldiamine EINECS 220-489-6 1,12-Diaminododecane Decanethylenediamine 1,12-diamino dodecane Dodecamethylenediamine MFCD00008155 1,12-Dodecanediamine

Density	0.9±0.1 g/cm3
Boiling Point	274.9±8.0 °C at 760 mmHg
Melting Point	67-69 °C(lit.)
Molecular Formula	C₁₂H₂₈N₂
Molecular Weight	200.364
Flash Point	155.0±0.0 °C
Exact Mass	200.225250
PSA	52.04000
LogP	3.23
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.465

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JR2200000

CHEMICAL NAME :: 1,12-Dodecanediamine

CAS REGISTRY NUMBER :: 2783-17-7

BEILSTEIN REFERENCE NO. :: 1742765

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C12-H28-N2

MOLECULAR WEIGHT :: 200.42

WISWESSER LINE NOTATION :: Z12Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,92,1990 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 670 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,92,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1088 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 43(5),18,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 330 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 43(5),18,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 440 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 43(5),18,1978 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 54600 ug/kg/26W-I

TOXIC EFFECTS :: Endocrine - changes in thymus weight Blood - change in clotting factors Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 43(5),18,1978

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H302-H314-H317
Precautionary Statements	P280-P305 + P351 + P338-P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	C: Corrosive;
Risk Phrases	R22;R36/37/38
Safety Phrases	S26-S36/37/39-S45
RIDADR	UN 3259 8/PG 3
WGK Germany	1
RTECS	JR2200000
Packaging Group	I; II; III
Hazard Class	8.0
HS Code	2921290000

113665-32-0

~54%

2783-17-7

Literature: Bartoli, Giuseppe; Di Antonio, Giustino; Giovannini, Riccardo; Giuli, Sandra; Lanari, Silvia; Paoletti, Melissa; Marcantoni, Enrico Journal of Organic Chemistry, 2008 , vol. 73, # 5 p. 1919 - 1924

4543-66-2

2783-17-7

Literature: Saotome,K. et al. Bulletin of the Chemical Society of Japan, 1966 , vol. 39, p. 480 - 484

2162-98-3

2783-17-7

Literature: Saotome,K. et al. Bulletin of the Chemical Society of Japan, 1966 , vol. 39, p. 480 - 484

4224-62-8

2783-17-7

Literature: Saotome,K. et al. Bulletin of the Chemical Society of Japan, 1966 , vol. 39, p. 480 - 484

38279-34-4

2783-17-7

Literature: Chemie Linz GmbH Patent: US5475141 A1, 1995 ;

67-66-3

2783-17-7

Literature: v. Braun; Anton Chemische Berichte, 1931 , vol. 64, p. 2867

64-17-5

4543-66-2

2783-17-7

Literature: v. Braun Chemische Berichte, 1909 , vol. 42, p. 4548

HS Code	2921290000
Summary	2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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