CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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XR1700000
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CHEMICAL NAME :
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Titanium
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CAS REGISTRY NUMBER :
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7440-32-6
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LAST UPDATED :
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199710
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DATA ITEMS CITED :
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12
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MOLECULAR FORMULA :
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Ti
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MOLECULAR WEIGHT :
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47.90
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WISWESSER LINE NOTATION :
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.TI
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intramuscular
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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114 mg/kg/77W-I
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TOXIC EFFECTS :
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Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - lymphoma, including Hodgkin's disease Tumorigenic - tumors at site of application
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REFERENCE :
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NCIUS* Progress Report for Contract No. PH-43-64-886, Submitted to the National Cancer Institute by The Institute of Chemical Biology, University of San Francisco. (San Francisco, CA 94117) Volume(issue)/page/year: PH43-64-886
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Intramuscular
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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360 mg/kg/69W-I
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TOXIC EFFECTS :
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Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - lymphoma, including Hodgkin's disease Tumorigenic - tumors at site of application
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REFERENCE :
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NCIUS* Progress Report for Contract No. PH-43-64-886, Submitted to the National Cancer Institute by The Institute of Chemical Biology, University of San Francisco. (San Francisco, CA 94117) Volume(issue)/page/year: PH43-64-886 ** REPRODUCTIVE DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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158 mg/kg
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SEX/DURATION :
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multigeneration
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TOXIC EFFECTS :
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Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death
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REFERENCE :
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AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,102,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 73255 No. of Facilities: 1060 (estimated) No. of Industries: 36 No. of Occupations: 42 No. of Employees: 21978 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5095 No. of Facilities: 9 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 250 (estimated) No. of Female Employees: 53 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5916 No. of Facilities: 6 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 1198 (estimated) No. of Female Employees: 400 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 73255 No. of Facilities: 11591 (estimated) No. of Industries: 113 No. of Occupations: 97 No. of Employees: 189763 (estimated) No. of Female Employees: 9744 (estimated)
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