1215071-06-9

1215071-06-9 structure

Name: Desmethylsildenafil-d8 citrate
Chemical Name: 5-[2-ethoxy-5-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one,2-hydroxypropane-1,2,3-tricarboxylic acid
CAS Number: 1215071-06-9
Molecular Formula: C₂₇H₂₈D₈N₆O₁₁S
Molecular Weight: 660.72300
Catalog: Research Areas Others
Create Date: 2017-06-14 11:09:52
Modify Date: 2024-01-02 19:26:16
Desmethylsildenafil-d8 (citrate) is the deuterium labeled Desmethylsildenafil citrate[1].

Name	5-[2-ethoxy-5-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one,2-hydroxypropane-1,2,3-tricarboxylic acid
Synonyms	[2H8]-N-Desmethyl Sildenafil citrate Desmethylsildenafil-d8 Citrate

Description	Desmethylsildenafil-d8 (citrate) is the deuterium labeled Desmethylsildenafil citrate[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.