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63644-62-2

63644-62-2 structure
63644-62-2 structure
  • Name: Coniferyl ferulate
  • Chemical Name: 3-(4-Hydroxy-3-methoxyphenyl)allyl 3-(4-hydroxy-3-methoxyphenyl)acrylate
  • CAS Number: 63644-62-2
  • Molecular Formula: C20H20O6
  • Molecular Weight: 356.369
  • Catalog: Biochemical Plant extracts
  • Create Date: 2018-07-17 20:53:50
  • Modify Date: 2024-01-03 13:36:24
  • Coniferyl ferulate, a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis, reverses multidrug resistance and downregulates P-glycoprotein. Coniferyl ferulate shows strong inhibition of human placental GST with an IC50 of 0.3 μM[1].

Name 3-(4-Hydroxy-3-methoxyphenyl)allyl 3-(4-hydroxy-3-methoxyphenyl)acrylate
Synonyms (2E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propen-1-yl (2E)-3-(4-hydroxy-3-methoxyphenyl)acrylate
2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (2E)-3-(4-hydroxy-3-methoxyphenyl)-2-propen-1-yl ester, (2E)-
[(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enyl] (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, 3-(4-hydroxy-3-methoxyphenyl)-2-propenyl ester
Description Coniferyl ferulate, a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis, reverses multidrug resistance and downregulates P-glycoprotein. Coniferyl ferulate shows strong inhibition of human placental GST with an IC50 of 0.3 μM[1].
Related Catalog
Target

Glutathione S-transferase[1] P-glycoprotein[1]

References

[1]. Chen C, et al. Coniferyl Ferulate, a Strong Inhibitor of Glutathione S-Transferase Isolated from Radix Angelicae sinensis, Reverses Multidrug Resistance and Downregulates P-Glycoprotein. Evid Based Complement Alternat Med. 2013;2013:639083.

Density 1.3±0.1 g/cm3
Boiling Point 570.5±50.0 °C at 760 mmHg
Molecular Formula C20H20O6
Molecular Weight 356.369
Flash Point 202.8±23.6 °C
Exact Mass 356.125977
PSA 85.22000
LogP 2.78
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.640
Storage condition 2-8C
HS Code 2918990090

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63644-62-2 structure

63644-62-2

Literature: RSC Advances, , vol. 3, # 44 p. 21964 - 21971

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63644-62-2 structure

63644-62-2

Literature: RSC Advances, , vol. 3, # 44 p. 21964 - 21971
HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%