DC Chemicals Limited
China
Product Name: Pholedrine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

370-14-9

370-14-9 structure

Name: Pholedrine
Chemical Name: rac Pholedrine
CAS Number: 370-14-9
Molecular Formula: C₁₀H₁₅NO
Molecular Weight: 165.23200
Catalog: analytical chemistry Standard Forensic and veterinary standards
Create Date: 2018-07-30 09:32:12
Modify Date: 2024-01-02 21:14:54
Pholedrine is an Autonomic Agent. It is a a sympathomimetic vasoconstrictive drug.

Name	rac Pholedrine
Synonyms	4-[2-(methylamino)propyl]phenol

Density	1.014g/cm3
Boiling Point	279.4ºC at 760mmHg
Melting Point	162-163°
Molecular Formula	C₁₀H₁₅NO
Molecular Weight	165.23200
Flash Point	109ºC
Exact Mass	165.11500
PSA	32.26000
LogP	1.93350
Index of Refraction	1.532
Storage condition	−20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SL8400000

CHEMICAL NAME :: Phenol, p-(2-(methylamino)propyl)-

CAS REGISTRY NUMBER :: 370-14-9

LAST UPDATED :: 199603

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H15-N-O

MOLECULAR WEIGHT :: 165.26

WISWESSER LINE NOTATION :: QR D1Y1&M1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Behavioral - changes in psychophysiological tests

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 159,442,1966

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,101,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 119 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 3,328,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 195,647,1940

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	26-36-45-36/37-16-7
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	SL8400000
HS Code	2922299090

770-39-8

74-89-5

370-14-9

Literature: Knoll A.G. Patent: DE674753 , 1936 ; DRP/DRBP Org.Chem.

103-86-6

370-14-9

Literature: Knoll A.G. Patent: DE672372 , 1936 ; DRP/DRBP Org.Chem.

50-00-0

103-86-6

370-14-9

Literature: Knoll A.G. Patent: DE672372 , 1936 ; DRP/DRBP Org.Chem.

7632-10-2

370-14-9

60-15-1

Literature: Blume Arzneimittel-Forschung/Drug Research, 1981 , vol. 31, # 5 p. 805 - 809

Precursor 4
770-39-8 74-89-5 103-86-6 50-00-0
DownStream 1
114860-09-2

HS Code	2922299090
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

370-14-9	3738-00-9
1286498-19-8	953-38-8
114860-09-2