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  • Product Name: PEG4 diazide
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  • Purity: 98.0%
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  • Contact: Tony Cao

101187-39-7

101187-39-7 structure
101187-39-7 structure
  • Name: Azido-PEG3-azide
  • Chemical Name: 1,11-Diazido-3,6,9-trioxaundecane
  • CAS Number: 101187-39-7
  • Molecular Formula: C8H16N6O3
  • Molecular Weight: 244.25100
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-04-01 19:45:54
  • Modify Date: 2024-01-02 11:59:58
  • Azido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1,11-Diazido-3,6,9-trioxaundecane
Synonyms 1-azido-2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethane
Description Azido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.1703g/mL
Boiling Point 163-196°C
Molecular Formula C8H16N6O3
Molecular Weight 244.25100
Exact Mass 244.12800
PSA 127.19000
LogP 0.56232
Storage condition -20°C
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
RIDADR NONH for all modes of transport

~88%

101187-39-7 structure

101187-39-7

Literature: WO2006/73314 A1, ; Page/Page column 31 ;

~92%

101187-39-7 structure

101187-39-7

Literature: Chemical Communications, , vol. 48, # 45 p. 5650 - 5652

~99%

101187-39-7 structure

101187-39-7

Literature: WO2008/11157 A2, ; Page/Page column 174 ;

~99%

101187-39-7 structure

101187-39-7

Literature: Tetrahedron, , vol. 65, # 36 p. 7385 - 7392

~15%

101187-39-7 structure

101187-39-7

Literature: Angewandte Chemie - International Edition, , vol. 51, # 9 p. 2151 - 2154

~99%

101187-39-7 structure

101187-39-7

Literature: Journal of the American Chemical Society, , vol. 127, # 36 p. 12434 - 12435