344299-49-6

344299-49-6 structure

Name: 1-Methylhistamine-d3 dihydrochloride
Chemical Name: n-tau-methyl-d3-histamine 2hcl
CAS Number: 344299-49-6
Molecular Formula: C₆H₁₀Cl₂D₃N₃
Molecular Weight: 201.11200
Catalog: Research Areas Metabolic Disease
Create Date: 2018-04-21 08:00:00
Modify Date: 2024-01-30 12:34:31
1-Methylhistamine-d3 (dihydrochloride) is the deuterium labeled 1-Methylhistamine (dihydrochloride)[1]. 1-Methylhistamine dihydrochloride is a histamine metabolite[2].

Name	n-tau-methyl-d3-histamine 2hcl
Synonyms	Nt-Methyl-d3-histaMine 2HCl N-Methyl-D3-histamineHCl NT-METHYL-D3-HISTAMINE DIHYDROCHLORIDE N'-Methyl-D3-histamine2HCl

Description	1-Methylhistamine-d3 (dihydrochloride) is the deuterium labeled 1-Methylhistamine (dihydrochloride)[1]. 1-Methylhistamine dihydrochloride is a histamine metabolite[2].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Saito K, et al. Determination of urinary excretion of histamine and 1-methylhistamine by liquid chromatography. J Chromatogr B Biomed Appl. 1994 Apr 1;654(2):270-5.